Asymmetric Direct Aldol Reaction Assisted by Water and a Proline‐Derived Tetrazole Catalyst
Asymmetric Direct Aldol Reaction Assisted by Water and a Proline‐Derived Tetrazole Catalyst
Torii, Hiromi; Nakadai, Masakazu; Ishihara, Kazuaki; Saito, Susumu; Yamamoto, Hisashi
2004-01-02 00:00:00
Just add water to improve the performance of direct aldol reactions like that shown. Previously, aldehydes with high water‐affinity or ‐solubility were considered unsuitable for asymmetric synthesis.
http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.pngAngewandte Chemie International EditionWileyhttp://www.deepdyve.com/lp/wiley/asymmetric-direct-aldol-reaction-assisted-by-water-and-a-proline-2dlPX0esOL
Asymmetric Direct Aldol Reaction Assisted by Water and a Proline‐Derived Tetrazole Catalyst
Just add water to improve the performance of direct aldol reactions like that shown. Previously, aldehydes with high water‐affinity or ‐solubility were considered unsuitable for asymmetric synthesis.
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