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Asymmetric Direct Aldol Reaction Assisted by Water and a Proline‐Derived Tetrazole Catalyst

Asymmetric Direct Aldol Reaction Assisted by Water and a Proline‐Derived Tetrazole Catalyst Just add water to improve the performance of direct aldol reactions like that shown. Previously, aldehydes with high water‐affinity or ‐solubility were considered unsuitable for asymmetric synthesis. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Angewandte Chemie International Edition Wiley

Asymmetric Direct Aldol Reaction Assisted by Water and a Proline‐Derived Tetrazole Catalyst

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References (1)

Publisher
Wiley
Copyright
Copyright © 2004 Wiley Subscription Services
ISSN
1433-7851
eISSN
1521-3773
DOI
10.1002/anie.200352724
pmid
15065280
Publisher site
See Article on Publisher Site

Abstract

Just add water to improve the performance of direct aldol reactions like that shown. Previously, aldehydes with high water‐affinity or ‐solubility were considered unsuitable for asymmetric synthesis.

Journal

Angewandte Chemie International EditionWiley

Published: Jan 2, 2004

Keywords: ; ; ; ;

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