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Biosensors and BiodetectionPhotodiode-Based Detection System for Biosensors

Biosensors and Biodetection: Photodiode-Based Detection System for Biosensors [Many sensors and biosensors are based on the detection of optical changes in the sensing phase. In order to build a stand-alone sensing device, a miniature and low-cost detection system is critical. Here, the method for manufacturing the most critical part (the photodetector) is described in detail. The receiver is based on a photodiode. The practical design of such device is presented here. By using it, it is possible to construct an optical sensor for fluorescence or absorption-based measurement. Discussed here are suitable methods for generation and modulation of probing light, as well as the possible optical configurations. Practical advice is given on the selection of the bandwidth, noise, amplification, etc. The described system was used for detection of green red fluorescent protein in E. coli during fermentation.] http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png

Biosensors and BiodetectionPhotodiode-Based Detection System for Biosensors

Part of the Methods in Molecular Biology™ Book Series (volume 503)
Editors: Rasooly, Avraham; Herold, Keith E.
Kostov, Yordan
Biosensors and Biodetection — Jan 1, 2009
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17 pages

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References (7)

Publisher
Humana Press
Copyright
© Humana Press 2009
ISBN
978-1-60327-566-8
Pages
307–323
DOI
10.1007/978-1-60327-567-5_17
Publisher site
See Chapter on Publisher Site

Abstract

[Many sensors and biosensors are based on the detection of optical changes in the sensing phase. In order to build a stand-alone sensing device, a miniature and low-cost detection system is critical. Here, the method for manufacturing the most critical part (the photodetector) is described in detail. The receiver is based on a photodiode. The practical design of such device is presented here. By using it, it is possible to construct an optical sensor for fluorescence or absorption-based measurement. Discussed here are suitable methods for generation and modulation of probing light, as well as the possible optical configurations. Practical advice is given on the selection of the bandwidth, noise, amplification, etc. The described system was used for detection of green red fluorescent protein in E. coli during fermentation.]

Published: Jan 1, 2009

Keywords: Optical sensor; Absorption sensor; Fluorescence sensor; Photodiode; Optical receiver

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