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TBP-TAF Complex SL1 Directs RNA Polymerase I Pre-initiation Complex Formation and Stabilizes Upstream Binding Factor at the rDNA Promoter*Journal of Biological Chemistry, 280
- Publisher
- Springer Journals
- Copyright
- Copyright © 2010 by Nature Publishing Group
- Subject
- Biomedicine; Biomedicine, general; Cancer Research
- ISSN
- 1474-175X
- eISSN
- 1474-1768
- DOI
- 10.1038/nrc2819
- Publisher site
- See Article on Publisher Site
Abstract
Recently, MYC has been shown to serve as a direct regulator of ribosome biogenesis and therefore coordinates protein synthesis. Could the regulation of ribosome biogenesis by MYC be necessary for its role in tumorigenesis?
Journal
Nature Reviews Cancer – Springer Journals
Published: Apr 1, 2010