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Exact Unconditional Sample Sizes for the 2 Times 2 Binomial Trial

Exact Unconditional Sample Sizes for the 2 Times 2 Binomial Trial SummaryExact attained significance level and sample size methods are developed for use with the unconditional Z statistic in the 2 times 2 contingency table from two independent binomial samples of equal size. The resulting sample sizes tend to be smaller than those required by tables for the exact conditional test. Moreover, the proposed exact Z test is uniformly more powerful than the exact conditional test for α = 0.01, 0.025 and 0.05, and common sample size n = 10(1)150, the only combinations of α and n considered herein. These methods therefore provide an exact approach to unconditional tests which, in contrast to the conditional ones, are easily explained to and under-stood by non-statisticians. This paper is the first for which sample size calculations are made based on exact unconditional tests for any situation in which no ancillary statistic exists for the nuisance parameter. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of the Royal Statistical Society Series A (Statistics in Society) Oxford University Press

Exact Unconditional Sample Sizes for the 2 Times 2 Binomial Trial

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References (26)

Copyright
© 1985 Royal Statistical Society
ISSN
0964-1998
eISSN
1467-985X
DOI
10.2307/2981892
Publisher site
See Article on Publisher Site

Abstract

SummaryExact attained significance level and sample size methods are developed for use with the unconditional Z statistic in the 2 times 2 contingency table from two independent binomial samples of equal size. The resulting sample sizes tend to be smaller than those required by tables for the exact conditional test. Moreover, the proposed exact Z test is uniformly more powerful than the exact conditional test for α = 0.01, 0.025 and 0.05, and common sample size n = 10(1)150, the only combinations of α and n considered herein. These methods therefore provide an exact approach to unconditional tests which, in contrast to the conditional ones, are easily explained to and under-stood by non-statisticians. This paper is the first for which sample size calculations are made based on exact unconditional tests for any situation in which no ancillary statistic exists for the nuisance parameter.

Journal

Journal of the Royal Statistical Society Series A (Statistics in Society)Oxford University Press

Published: Dec 5, 2018

Keywords: ancillary statistics; conditionality principle; exact unconditional test; fisher’s exact test; power; two by two contingency tables

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