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ORIGINAL ARTICLE Impact of Operative Blood Loss on Survival in Invasive Ductal Adenocarcinoma of the Pancreas Shunji Nagai, MD, PhD,* Tsutomu Fujii, MD, PhD,* Yasuhiro Kodera, MD, PhD,* Mitsuro Kanda, MD, PhD,* Tevfik T. Sahin, MD,* Akiyuki Kanzaki, MD,* Suguru Yamada, MD, PhD,* Hiroyuki Sugimoto, MD, PhD,* Shuji Nomoto, MD, PhD,* Shin Takeda, MD, PhD,* Satoshi Morita, PhD,Þ and Akimasa Nakao, MD, PhD* The following factors have been reported to be associated Objectives: The aim of this study was to determine the prognostic with overall survival in pancreatic cancer: patient demographics factors and assess the impact of excessive operative blood loss (OBL) such as age and sex; histopathologic factors such as tumor size, on survival after pancreatectomy for invasive ductal adenocarcinoma. differentiation, blood vessel or neural invasion, lymph node Methods: From the retrospective analysis, 271 patients were eligible status, and resection margins; and perioperative factors such for evaluation. Overall survival was assessed to clarify the prognostic as type of resection, operative blood loss (OBL), red blood cell determinants, including patient characteristics, perioperative factors, and transfusion, operation time, era of resection, and chemother- 4Y15 tumor characteristics. apy. Operative blood loss and red blood cell transfusion are Results: The overall survival
Pancreas – Wolters Kluwer Health
Published: Jan 1, 2011
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