journal article
LitStream Collection
doi: 10.1007/BF03014190pmid: 13608306
The results of some experimental work with the cardiac sphincter mechanism of cats and dogs are reported. Several methods of investigation were employed. (a) The peristaltic reflex of the lower end of the oesophagus was elicited by steady or rhythmic inflation of a balloon in the area. The tone was also determined. (b) The compliance of the cardiac sphincter to perfusion from the stomach was examined, with and without gastric dilatation. The results indicated that gastric dilatation is an important factor in regurgitation.
doi: 10.1007/BF03014191pmid: 13608307
The hypotensive action of Fluothane in cats receiving autonomic blocking agents was compared with the response in unblocked cats. No effect on reflex mechanisms, the vasomotor centre, sympathetic ganglia, or nerve endings appears to play any part in the production of hypotension in the cat. Cardiac output in the intact animal receiving Fluothane was measured. From a consideration of both groups of experiments it would seem likely that Fluothane exerts its hypotensive effect by means of action on the heart and the arterioles. Coincident depression of respiration occurs.
Crandell, D.; Hollandsworth, Luther; Whitcher, Charles
doi: 10.1007/BF03014192pmid: 13608308
An outline of the management of severe systemic tetanus has been presented. Special emphasis has been given to the control of reflex muscle spasm and to the maintenance of adequate pulmonary ventilation. A sedative-relaxant regimen consisting of secobarbital or pentobarbital, methocarbamol, and chlorpromazine administered intravenously has been advocated. The anaesthesiologist, with. his knowledge of the pharmacological application of drugs and of the physiological maintenance of pulmonary ventilation, can play a vital role in the management of severe systemip tetanus.
doi: 10.1007/BF03014193pmid: 13608309
In the hope of reducing the incidence of pneumothorax associated with brachial plexus block anaesthesia, a short-needle technique, using the supraclavicular approach, is described and the results in 82 eases are analysed.
doi: 10.1007/BF03014194pmid: 13608310
Metliohexital is the only intravenous anaesthetic agent tested by us so far which combines shorter action with a higher potency than thiopental. If dose per minute of anaesthesia for a standard procedure is taken as an indication, the relative potency of thiopental to methohexital is 1:1.54. Nevertheless, the ratio of total sleep time per minute of anaesthesia for thiopental and methohexital is 1:0.7.
doi: 10.1007/BF03014195pmid: 13608311
The effect of anticholinergic drugs on the cardiac vagus was studied by means of monitoring the electrocardiogram (lead 2), the radial pulse (palpation), and the apical heart beat (auscultation) in 66 mentally disturbed patients before, during, and after 396 unmodified and modified electroshock treatments. It was suspected, but could not be demonstrated unequivocally, that a period of cardiac asystole occurred when no anticholinergic drug was given. Premedication with an anticholinergic drug reduced potentially dangerous cardiac arrhythmias that followed ECT .
doi: 10.1007/BF03014196pmid: 13608312
A record has been kept on the effect of dipipanone hydrochloride on four hundred postoperative patients, noting the dose, the time intervals between injection and satisfactory effect, and between the injection and subsequent use of sedation, and any side effects on blood pressure, pulse, respiration, and nausea or vomiting.
Davenport, Harold; Rosales, Jose
doi: 10.1007/BF03014197pmid: 13608313
Some significant anatomical and anaesthetic problems associated with direct laryngoscopy and endotracheal intubation in infants and children are considered.
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