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- Publisher
- Wiley
- Copyright
- Copyright © 2011 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim
- ISSN
- 1613-6810
- eISSN
- 1613-6829
- DOI
- 10.1002/smll.201100567
- pmid
- 21678552
- Publisher site
- See Article on Publisher Site
Abstract
Morphology‐dependent drug loading capacities and release kinetics are observed from pH‐responsive diblock copolymer‐based nano‐objects, derived from the same block copolymer precursor. Shell‐crosslinked, rod‐shaped nanostructures exhibit a higher doxorubicin‐loading capacity and rate of release than do their spherical counterparts. The extent of crosslinking and the type of crosslinker is also demonstrated to affect the rate of release.
Journal
Small – Wiley
Published: Jul 18, 2011