The Growing Burden of Pulmonary Hypertension in the Modern Era

The Growing Burden of Pulmonary Hypertension in the Modern Era EDITORIAL The Growing Burden of Pulmonary Hypertension in the Modern Era A Zebra No More? See Article by Wijeratne et al. Stephen C. Mathai, MD, MHS John J. Ryan, MD ulmonary hypertension (PH) is a heterogeneous syndrome characterized by elevated pulmonary pressures. Although often suspected based on symp- P toms of dyspnea and elevated estimates of pulmonary arterial systolic pres- sures on echocardiogram, PH can only be diagnosed by right heart catheterization demonstrating a mean pulmonary artery pressure ≥25 mm Hg. Clinically, PH can result from various comorbid conditions, including underlying cardiac, pulmonary, thromboembolic, and miscellaneous diseases. PH in the absence of these comorbid conditions constitutes a small subset of PH, known as pulmonary arterial hyperten- sion (PAH). Over the last several years, determining the incidence and prevalence of PH in population-based studies has proven challenging, in part, because of the lack of specificity of diagnosis codes commonly used in reimbursement system data- bases. These codes do not align with the current classification system and thus are unable to accurately distinguish disease phenotypes. In addition, proper clas- sification of PH, according to guideline recommendations, requires not only a high clinical suspicion but also extensive targeted testing, which is often http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Circulation: Cardiovascular Quality & Outcomes Wolters Kluwer Health

The Growing Burden of Pulmonary Hypertension in the Modern Era

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Publisher
Wolters Kluwer
Copyright
© 2018 American Heart Association, Inc.
ISSN
1941-7705
eISSN
1941-7713
D.O.I.
10.1161/CIRCOUTCOMES.118.004536
Publisher site
See Article on Publisher Site

Abstract

EDITORIAL The Growing Burden of Pulmonary Hypertension in the Modern Era A Zebra No More? See Article by Wijeratne et al. Stephen C. Mathai, MD, MHS John J. Ryan, MD ulmonary hypertension (PH) is a heterogeneous syndrome characterized by elevated pulmonary pressures. Although often suspected based on symp- P toms of dyspnea and elevated estimates of pulmonary arterial systolic pres- sures on echocardiogram, PH can only be diagnosed by right heart catheterization demonstrating a mean pulmonary artery pressure ≥25 mm Hg. Clinically, PH can result from various comorbid conditions, including underlying cardiac, pulmonary, thromboembolic, and miscellaneous diseases. PH in the absence of these comorbid conditions constitutes a small subset of PH, known as pulmonary arterial hyperten- sion (PAH). Over the last several years, determining the incidence and prevalence of PH in population-based studies has proven challenging, in part, because of the lack of specificity of diagnosis codes commonly used in reimbursement system data- bases. These codes do not align with the current classification system and thus are unable to accurately distinguish disease phenotypes. In addition, proper clas- sification of PH, according to guideline recommendations, requires not only a high clinical suspicion but also extensive targeted testing, which is often

Journal

Circulation: Cardiovascular Quality & OutcomesWolters Kluwer Health

Published: Feb 1, 2018

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