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FIGURE 1. Forest plot for study-specific and pooled RR and 95% CI of survival for metformin users and nonusers. A diamond data marker represents the overall RR and 95% CI for the outcome of interest
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Pancreas Volume 47, Number 3, March 2018 Letters to the Editor multicenter survey. Endoscopy.2007;39: 4 cases of pancreatitis (1.98%). In these P = 0.01) (Fig. 1). The statistical hetero- 613–615. cases, the admission length of stay was 4, geneity was moderate with I of 58% 7, 14, and 15 days. This subgroup of patients (P = 0.02). 7. Möschler O, May A, Müller MK, et al. heterogeneity with pancreatitis had a significantly longer Theoretically, metformin was found Complications in and performance of inpatient stay than that noted by Wadhwa double-balloon enteroscopy (DBE): results to have antineoplastic properties through et al. Therefore, perhaps further study is re- from a large prospective DBE database in several mechanisms in in vitro studies. Germany. Endoscopy. 2011;43:484–489. quired in understanding the length of stay in Pancreatic cancer cells are supposedly hospital and therefore cost by subdividing stimulated by insulin-like growth factor 8. Jovanovic I, Vormbrock K, Zimmermann L, pancreatitis by etiology. et al. Therapeutic double-balloon enteroscopy: 1(IGF-1). Whole body production and In conclusion, DBE is an iatrogenic a binational, three-center experience. Dig Dis. sensitivity of IGF-1 are increased by cause of acute pancreatitis. It is of interest 2011;29(suppl 1):27–31. hyperinsulinemic states. Metformin decreases that
Pancreas – Wolters Kluwer Health
Published: Jan 1, 2018
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