Circulation RESEARCH LETTER Myocardial Scar Is Prevalent and Associated With Subclinical Myocardial Dysfunction in Women With Suspected Ischemia But No Obstructive Coronary Artery Disease From the Women’s Ischemia Syndrome Evaluation–Coronary Vascular Dysfunction Study omen with suspected ischemia and no obstructive coronary artery dis- Janet Wei, MD ease (INOCA) have a high prevalence of coronary microvascular dysfunc- May Bakir, MD Wtion and an elevated rate of major adverse cardiac events, including Navid Darounian, MD nonfatal myocardial infarction (MI). Cardiac magnetic resonance (CMR) with late Quanlin Li, MS gadolinium enhancement (LGE) imaging accurately visualizes and characterizes Sofy Landes, MD myocardial scar, which predicts major adverse cardiac events. The prevalence, in- Puja K. Mehta, MD cidence, and scar pattern in women with INOCA is not well characterized. We Chrisandra L. Shufelt, MD evaluated LGE in women with suspected INOCA in the WISE-CVD study (Women’s Eileen M. Handberg, PhD Ischemia Syndrome Evaluation–Coronary Vascular Dysfunction; URL: http://www. Sheryl F. Kelsey, MD clinicaltrials.gov. Unique identifier: NCT00832702). George Sopko, MD Participants in the WISE-CVD study included women with suspected INOCA as Carl J. Pepine, MD previously described. The study was approved by the site institutional review com- John W. Petersen, MD mittees. All participants gave informed
Circulation – Wolters Kluwer Health
Published: Feb 20, 2018
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
All the latest content is available, no embargo periods.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud