Access the full text.
Sign up today, get DeepDyve free for 14 days.
J. Kalita, G. Kumar, V. Bansal, U. Misra (2009)
Relationship of homocysteine with other risk factors and outcome of ischemic strokeClinical Neurology and Neurosurgery, 111
I. Graham, Leslie Daly, H. Refsum, Killian Robinson, L. Brattström, P. Ueland, R. Palma-Reis, G. Boers, Richard Sheahan, Bo Israelsson, C. Uiterwaal, R. Meleady, Dorothy McMaster, Petra Verhoef, J. Witteman, P. Rubba, Hélène Bellet, Jan Wautrecht, Harold Valk, A. Luis, Francoise Parrot-Roulaud, Kok Tan, I. Higgins, Danielle Garcon, Maria Medrano, Mirande Candito, Alun Evans, Generoso Andria (1997)
Plasma homocysteine as a risk factor for vascular disease. The European Concerted Action Project.JAMA, 277 22
Ling Hao, Jing Ma, Jiang-hui Zhu, M. Stampfer, Yi-hua Tian, W. Willett, Zhu Li (2007)
High prevalence of hyperhomocysteinemia in Chinese adults is associated with low folate, vitamin B-12, and vitamin B-6 status.The Journal of nutrition, 137 2
D. Wald, Lucy Bishop, N. Wald, M. Law, Enid Hennessy, D. Weir, J. Mcpartlin, J. Scott (2001)
Randomized trial of folic acid supplementation and serum homocysteine levels.Archives of internal medicine, 161 5
Y. Huo, Jianping Li, X. Qin, Yining Huang, Xiaobin Wang, R. Gottesman, Genfu Tang, Bin-yan Wang, Dafang Chen, M. He, Jia Fu, Yefeng Cai, Xiuli Shi, Yan Zhang, Yi-min Cui, N. Sun, Xiaoying Li, Xiaoshu Cheng, Jian'an Wang, Xinchun Yang, Tianlun Yang, C. Xiao, Gang Zhao, Q. Dong, Dingliang Zhu, Xian Wang, J. Ge, Lianyou Zhao, D. Hu, Li-sheng Liu, F. Hou (2015)
Efficacy of folic acid therapy in primary prevention of stroke among adults with hypertension in China: the CSPPT randomized clinical trial.JAMA, 313 13
J. Armitage, L. Bowman, R. Clarke, K. Wallendszus, R. Bulbulia, K. Rahimi, R. Haynes, S. Parish, P. Sleight, R. Peto, R. Collins (2010)
Effects of homocysteine-lowering with folic acid plus vitamin B12 vs placebo on mortality and major morbidity in myocardial infarction survivors: a randomized trial.JAMA, 303 24
Jianping Li, Shanqun Jiang, Yan Zhang, Genfu Tang, Yu Wang, G. Mao, Zhiping Li, Xiping Xu, Bin-yan Wang, Y. Huo (2015)
H-type hypertension and risk of stroke in chinese adults: A prospective, nested case–control studyJournal of Translational Internal Medicine, 3
Chunyan Zhang, Xiaobin Wang, M. He, X. Qin, Genfu Tang, Xin Xu, Yu Wang, Y. Huo, Yefeng Cai, Jia Fu, Gang Zhao, Q. Dong, Xiping Xu, Bin-yan Wang, F. Hou (2015)
Proteinuria Is an Independent Risk Factor for First Incident Stroke in Adults Under Treatment for Hypertension in ChinaJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 4
A. Bostom, M. Carpenter, J. Kusek, A. Levey, L. Hunsicker, M. Pfeffer, J. Selhub, P. Jacques, E. Cole, L. Gravens-Mueller, A. House, C. Kew, J. McKenney, Á. Pacheco-Silva, T. Pesavento, J. Pirsch, Stephen Smith, S. Solomon, M. Weir (2011)
Homocysteine-Lowering and Cardiovascular Disease Outcomes in Kidney Transplant Recipients: Primary Results From the Folic Acid for Vascular Outcome Reduction in Transplantation TrialCirculation, 123
J. Meschia, C. Bushnell, B. Boden-Albala, L. Braun, D. Bravata, S. Chaturvedi, M. Creager, R. Eckel, M. Elkind, M. Fornage, L. Goldstein, S. Greenberg, Susanna Horvath, C. Iadecola, E. Jauch, W. Moore, John Wilson (2011)
Guidelines for the Primary Prevention of Stroke: A Statement for Healthcare Professionals From the American Heart Association/American Stroke AssociationStroke, 45
S. Moll, E. Varga (2005)
Homocysteine and MTHFR Mutations.Circulation, 132 1
G. Hankey, J. Eikelboom (2005)
Homocysteine and strokeThe Lancet, 365
K. Albright, Amelia Boehme, R. Tanner, J. Blackburn, G. Howard, Virginia Howard, M. Safford, Mark Beasley, N. Limdi (2016)
Addressing Stroke Risk Factors in Black and White Americans: Findings from the National Health and Nutrition Examination Survey, 2009-2010.Ethnicity & disease, 26 1
Sandra Gomes, C. Lopes, E. Pinto (2015)
Folate and folic acid in the periconceptional period: recommendations from official health organizations in thirty-six countries worldwide and WHOPublic Health Nutrition, 19
Yifan Huang, Yong-han He, Xiaowei Sun, Yujie He, Y. Li, Changhao Sun (2014)
Maternal High Folic Acid Supplement Promotes Glucose Intolerance and Insulin Resistance in Male Mouse Offspring Fed a High-Fat DietInternational Journal of Molecular Sciences, 15
P. Tighe, M. Ward, H. McNulty, Owen Finnegan, A. Dunne, J. Strain, A. Molloy, M. Duffy, K. Pentieva, J. Scott (2011)
A dose-finding trial of the effect of long-term folic acid intervention: implications for food fortification policy.The American journal of clinical nutrition, 93 1
Yanping Li, Dong Wang, S. Ley, A. Howard, Yu-na He, Yuan Lu, G. Danaei, F. Hu (2016)
Potential Impact of Time Trend of Life-Style Factors on Cardiovascular Disease Burden in China.Journal of the American College of Cardiology, 68 8
R. Buettner, I. Bettermann, Christine Hechtl, E. Gäbele, C. Hellerbrand, J. Schölmerich, L. Bollheimer (2010)
Dietary Folic Acid Activates AMPK and Improves Insulin Resistance and Hepatic Inflammation in Dietary Rodent Models of the Metabolic SyndromeHormone and Metabolic Research, 42
L. Lee, S. Shahar, N. Rajab (2009)
Serum folate concentration, cognitive impairment, and DNA damage among elderly individuals in Malaysia.Nutrition research, 29 5
E. Rimm, W. Willett, F. Hu, L. Sampson, G. Colditz, J. Manson, C. Hennekens, M. Stampfer (1998)
Folate and vitamin B6 from diet and supplements in relation to risk of coronary heart disease among women.JAMA, 279 5
X. Qin, Youbao Li, N. Sun, Hong Wang, Yan Zhang, Jiguang Wang, Jianping Li, Xin Xu, M. Liang, Jing Nie, Bin-yan Wang, Xiaoshu Cheng, Nan-fang Li, Yingxian Sun, Lianyou Zhao, Xiaobin Wang, F. Hou, Y. Huo (2017)
Elevated Homocysteine Concentrations Decrease the Antihypertensive Effect of Angiotensin-Converting Enzyme Inhibitors in Hypertensive PatientsArteriosclerosis, Thrombosis, and Vascular Biology, 37
M. Holmes, P. Newcombe, J. Hubacek, R. Sofat, S. Ricketts, J. Cooper, M. Breteler, L. Bautista, Pankaj Sharma, J. Whittaker, L. Smeeth, F. Fowkes, A. Algra, V. Shmeleva, Z. Szolnoki, M. Roest, M. Linnebank, J. Zacho, M. Nalls, A. Singleton, L. Ferrucci, J. Hardy, B. Worrall, S. Rich, M. Matarin, P. Norman, L. Flicker, O. Almeida, F. Bockxmeer, H. Shimokata, K. Khaw, N. Wareham, M. Bobák, J. Sterne, G. Smith, P. Talmud, C. Duijn, S. Humphries, J. Price, S. Ebrahim, D. Lawlor, G. Hankey, J. Meschia, M. Sandhu, A. Hingorani, J. Casas (2011)
Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trialsLancet, 378
K. Bønaa, I. Njølstad, P. Ueland, H. Schirmer, A. Tverdal, T. Steigen, Harald Wang, J. Nordrehaug, E. Arnesen, K. Rasmussen (2006)
Homocysteine lowering and cardiovascular events after acute myocardial infarction.The New England journal of medicine, 354 15
S. Zoungas, B. McGrath, P. Branley, P. Kerr, C. Muske, R. Wolfe, R. Atkins, K. Nicholls, M. Fraenkel, B. Hutchison, R. Walker, J. McNeil (2006)
Cardiovascular morbidity and mortality in the Atherosclerosis and Folic Acid Supplementation Trial (ASFAST) in chronic renal failure: a multicenter, randomized, controlled trial.Journal of the American College of Cardiology, 47 6
R. Clarke, J. Halsey, S. Lewington, E. Lonn, J. Armitage, J. Manson, K. Bønaa, J. Spence, O. Nygård, R. Jamison, J. Gaziano, P. Guarino, D. Bennett, Fraz Mir, R. Peto, R. Collins (2010)
Effects of lowering homocysteine levels with B vitamins on cardiovascular disease, cancer, and cause-specific mortality: Meta-analysis of 8 randomized trials involving 37 485 individuals.Archives of internal medicine, 170 18
G. Boysen, T. Brander, H. Christensen, R. Gideon, T. Truelsen (2003)
Homocysteine and Risk of Recurrent StrokeStroke: Journal of the American Heart Association, 34
G. Hankey (2010)
B vitamins in patients with recent transient ischaemic attack or stroke in the VITAmins TO Prevent Stroke (VITATOPS) trial: a randomised, double-blind, parallel, placebo-controlled trialThe Lancet Neurology, 9
W. Herrmann, R. Obeid, H. Schorr, Wafika Zarzour, J. Geisel (2003)
Homocysteine, Methylenetetrahydrofolate Reductase C677T Polymorphism and the B-Vitamins: A Facet of Nature-Nurture Interplay, 41
Yun Song, B. Xu, Richard Xu, R. Tung, Eric Frank, Wayne Tromble, Tong Fu, Weiyi Zhang, Tao Yu, Chunyan Zhang, F. Fan, Yan Zhang, Jianping Li, H. Bao, Xiaoshu Cheng, X. Qin, Genfu Tang, Yundai Chen, Tianlun Yang, N. Sun, Xiaoying Li, Lianyou Zhao, F. Hou, J. Ge, Q. Dong, Bin-yan Wang, Xiping Xu, Y. Huo (2016)
Independent and Joint Effect of Brachial-Ankle Pulse Wave Velocity and Blood Pressure Control on Incident Stroke in Hypertensive AdultsHypertension, 68
J. Toole, M. Malinow, L. Chambless, J. Spence, L. Pettigrew, Ron Howard, Elizabeth Sides, Christina Wang, M. Stampfer, T. Erlinger, E. Platz, N. Rifai, K. Helzlsouer, T. Shinoda-Tagawa, Robert Leonard, Jean Pontikas, J. McDonough, David Allen, P. Dreyer (2004)
Lowering homocysteine in patients with ischemic stroke to prevent recurrent stroke, myocardial infarction, and death: the Vitamin Intervention for Stroke Prevention (VISP) randomized controlled trial.JAMA, 291 5
P. Ganguly, S. Alam (2015)
Role of homocysteine in the development of cardiovascular diseaseNutrition Journal, 14
C. Anderson, S. Jee, J. Charleston, Matthew Narrett, L. Appel (2010)
Effects of folic acid supplementation on serum folate and plasma homocysteine concentrations in older adults: a dose-response trial.American journal of epidemiology, 172 8
Jeongseon Kim, Y. Cho, Dong-Hyun Kim, Bong-Hwa Lee, D. Hwang, Jin-Ju Jeong, Hun-Jae Lee, K. Matsuo, K. Tajima, Y. Ahn (2012)
Dietary intake of folate and alcohol, MTHFR C677T polymorphism, and colorectal cancer risk in Korea.The American journal of clinical nutrition, 95 2
K. Mccully (2015)
Homocysteine and the pathogenesis of atherosclerosisExpert Review of Clinical Pharmacology, 8
X. Qin, Jianping Li, Yi-min Cui, Zeyuan Liu, Zhigang Zhao, J. Ge, De-ming Guan, Jian Hu, Yan-ni Wang, Fu-min Zhang, Xin Xu, Xiaobin Wang, Xiping Xu, Y. Huo (2012)
Effect of folic acid intervention on the change of serum folate level in hypertensive Chinese adults: do methylenetetrahydrofolate reductase and methionine synthase gene polymorphisms affect therapeutic responses?Pharmacogenetics and Genomics, 22
Shanqun Jiang, Jianping Li, Yan Zhang, S. Venners, Genfu Tang, Yu Wang, Zhiping Li, Xiping Xu, Bin-yan Wang, Y. Huo (2017)
Methylenetetrahydrofolate reductase C677T polymorphism, hypertension and risk of stroke: a prospective, nested case-control studyInternational Journal of Neuroscience, 127
Quanhe Yang, Lynn Bailey, R. Clarke, W. Flanders, Tiebin Liu, Ajay Yesupriya, M. Khoury, J. Friedman (2012)
Prospective study of methylenetetrahydrofolate reductase (MTHFR) variant C677T and risk of all-cause and cardiovascular disease mortality among 6000 US adults.The American journal of clinical nutrition, 95 5
Andrew House, M. Eliasziw, Daniel Cattran, David Churchill, Matthew Oliver, A. Fine, George Dresser, J. Spence (2010)
Effect of B-vitamin therapy on progression of diabetic nephropathy: a randomized controlled trial.JAMA, 303 16
S. Mendis, Stephen Davis, B. Norrving (2015)
Organizational update: the world health organization global status report on noncommunicable diseases 2014; one more landmark step in the combat against stroke and vascular disease.Stroke, 46 5
R. Clarke, J. Halsey, D. Bennett, S. Lewington (2011)
Homocysteine and vascular disease: review of published results of the homocysteine-lowering trialsJournal of Inherited Metabolic Disease, 34
A. Towfighi, D. Markovic, B. Ovbiagele (2010)
Pronounced association of elevated serum homocysteine with stroke in subgroups of individuals: A nationwide studyJournal of the Neurological Sciences, 298
Xin Xu, X. Qin, Youbao Li, Dan Sun, Jun Wang, M. Liang, Bin-yan Wang, Y. Huo, F. Hou (2016)
Efficacy of Folic Acid Therapy on the Progression of Chronic Kidney Disease: The Renal Substudy of the China Stroke Primary Prevention Trial.JAMA internal medicine, 176 10
Margaret McDowell, D. Lacher, Christine Pfeiffer, Joseph Mulinare, M. Picciano, Jeanne Rader, E. Yetley, J. Kennedy-Stephenson, Clifford Johnson (2008)
Blood folate levels: the latest NHANES results.NCHS data brief, 6
D. Kennedy, Seth Stern, M. Moretti, I. Matok, M. Sarkar, C. Nickel, G. Koren (2011)
Folate intake and the risk of colorectal cancer: a systematic review and meta-analysis.Cancer epidemiology, 35 1
Supplemental Digital Content is available in the text.
Arteriosclerosis, Thrombosis, and Vascular Biology – Wolters Kluwer Health
Published: Mar 1, 2018
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.