Laparoscopic gastrectomy for elderly patients with gastric cancer

Laparoscopic gastrectomy for elderly patients with gastric cancer AbstractBackground:Laparoscopic gastrectomy (LG) has been widely applied in patients with gastric cancer (GC). However, the safety and application value of LG in elderly patients with GC was still unclear. In this study, we aimed to evaluate the feasibility and safety of LG for elderly patients with GC using the meta-analysis.Methods:Studies comparing elderly patients and nonelderly patients who underwent LG for GC were reviewed and collected from the PubMed, EBSCO, Cochrane Library, and EMBASE. Outcomes such as operative results, postoperative recovery, and morbidity were compared and analyzed. The Review Manager 5.3 was used to portray the weighted mean difference (WMD) and odds ratio (OR) with a 95% confidence interval (CI).Results:Eleven observational studies with a total of 3275 patients were included. Compared with nonelderly patients, elderly patients had shorter operation time (WMD −10.46; 95% CI −17.06 to −3.86; P = .002), less retrieved lymph nodes (WMD −2.34; 95% CI −3.77 to −0.92; P = .001), delayed time to first flatus (WMD 0.31; 95% CI 0.10–0.51; P = .003), longer postoperative hospital stays (WMD 1.06; 95% CI 0.07–2.05; P = .04), higher risk for overall postoperative complication (OR 1.34; 95% CI 1.08–1.67; P = .009), nonsurgical postoperative complication (OR 1.98; 95% CI 1.24–3.15; P = .004), and postoperative pulmonary complication (OR: 3.09; 95% CI 1.68–5.68; P < .001). There was no significance between nonelderly patients and elderly patients regarding the estimated blood loss, incidences of surgical postoperative complication, surgical site infection, and ileus (P > .05).Conclusion:Outcomes of LG for elderly patients were comparable to those in nonelderly patients. Age alone should not preclude LG in elderly patients. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Medicine Wolters Kluwer Health

Laparoscopic gastrectomy for elderly patients with gastric cancer

Loading next page...
 
/lp/wolters_kluwer/laparoscopic-gastrectomy-for-elderly-patients-with-gastric-cancer-KeNWF1xG7X
Publisher
Wolters Kluwer
Copyright
Copyright © 2018 the Author(s). Published by Wolters Kluwer Health, Inc.
ISSN
0025-7974
eISSN
1536-5964
D.O.I.
10.1097/MD.0000000000010007
Publisher site
See Article on Publisher Site

Abstract

AbstractBackground:Laparoscopic gastrectomy (LG) has been widely applied in patients with gastric cancer (GC). However, the safety and application value of LG in elderly patients with GC was still unclear. In this study, we aimed to evaluate the feasibility and safety of LG for elderly patients with GC using the meta-analysis.Methods:Studies comparing elderly patients and nonelderly patients who underwent LG for GC were reviewed and collected from the PubMed, EBSCO, Cochrane Library, and EMBASE. Outcomes such as operative results, postoperative recovery, and morbidity were compared and analyzed. The Review Manager 5.3 was used to portray the weighted mean difference (WMD) and odds ratio (OR) with a 95% confidence interval (CI).Results:Eleven observational studies with a total of 3275 patients were included. Compared with nonelderly patients, elderly patients had shorter operation time (WMD −10.46; 95% CI −17.06 to −3.86; P = .002), less retrieved lymph nodes (WMD −2.34; 95% CI −3.77 to −0.92; P = .001), delayed time to first flatus (WMD 0.31; 95% CI 0.10–0.51; P = .003), longer postoperative hospital stays (WMD 1.06; 95% CI 0.07–2.05; P = .04), higher risk for overall postoperative complication (OR 1.34; 95% CI 1.08–1.67; P = .009), nonsurgical postoperative complication (OR 1.98; 95% CI 1.24–3.15; P = .004), and postoperative pulmonary complication (OR: 3.09; 95% CI 1.68–5.68; P < .001). There was no significance between nonelderly patients and elderly patients regarding the estimated blood loss, incidences of surgical postoperative complication, surgical site infection, and ileus (P > .05).Conclusion:Outcomes of LG for elderly patients were comparable to those in nonelderly patients. Age alone should not preclude LG in elderly patients.

Journal

MedicineWolters Kluwer Health

Published: Feb 1, 2018

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off