LETTERS TO THE EDITOR Recently, I have reported that human to establish mature-form islets in ad- Human Fetal β Islets Express pancreatic islets develop through fusion be- vanced fusion? Do the β islets remain Coagulation Factor XIII-A tween 2 distinct precursor islets, β and α/δ passive in the process? For the questions, islets. The β islets consist of only insulin- I raised a hypothesis that the β islets and Proteases Suggesting producing cells, whereas the α/δ islets consist regulated the fusion by secreting nonendo- Amphicrine Regulation to of intermixed glucagon- and somatostatin- crine soluble factors. In this study, po- Facilitate Islet Fusion producing cells. They are evidently discern- tential soluble factor candidates were able on hematoxylin and eosin sections. screened in human fetal pancreatic islets The β islets are global in shape surrounded using immunohistochemistry. by well-developed fibrous capsule. In con- Formalin-fixed and paraffin-embedded To the Editor: trast, the α/δ islets are variable in shape and tissue samples of 36 fetal autopsies, ranging ancreatic islet development has been incompletely encapsulated, suggesting an from 12 to 29 weeks of gestational age, were P a subject of intense biomedical inter- active mobility. As the α/δ islets adjoin collected randomly from pathology
Pancreas – Wolters Kluwer Health
Published: Jan 1, 2018
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera