Gallstone disease, towards a better understanding and clinical practice

Gallstone disease, towards a better understanding and clinical practice EDITORIAL URRENT Gallstone disease, towards a better understanding PINION and clinical practice a,b Chantal Housset Among all digestive diseases, gallstone disease is the (NAFLD) have been identified as potential targets, in most common and costly one, with an estimated the prevention of cholesterol gallstone disease. Arr- prevalence of 10–20% in the Western world. Symp- ese et al. herein describe the frequent association tomatic disease is responsible for 1.4 million visits and bidirectional relationship between gallstone and 750 000 cholecystectomies per year in the disease and NAFLD. Insulin resistance, a well estab- United States. The vast majority of gallstones (more lished key event in the development and progres- than 75%) are of cholesterol or cholesterol-predom- sion of NAFLD, has also been shown to cause inant type. In this issue of Current Opinion in cholesterol gallstone formation. In addition, apart Gastroenterology, Shabanzadeh reports on the epi- from common risk factors, NAFLD has been identi- demiology of gallstone disease on the basis of ultra- fied as an independent risk factor of gallstone sound screening, notably in population cohorts disease. Conversely gallstone disease and cholecys- unaware of the presence of gallstones. These studies tectomy have an impact on the development and indicate that http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Opinion in Gastroenterology Wolters Kluwer Health

Gallstone disease, towards a better understanding and clinical practice

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Publisher
Wolters Kluwer Health
Copyright
Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved.
ISSN
0267-1379
eISSN
1531-7056
D.O.I.
10.1097/MOG.0000000000000425
Publisher site
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Abstract

EDITORIAL URRENT Gallstone disease, towards a better understanding PINION and clinical practice a,b Chantal Housset Among all digestive diseases, gallstone disease is the (NAFLD) have been identified as potential targets, in most common and costly one, with an estimated the prevention of cholesterol gallstone disease. Arr- prevalence of 10–20% in the Western world. Symp- ese et al. herein describe the frequent association tomatic disease is responsible for 1.4 million visits and bidirectional relationship between gallstone and 750 000 cholecystectomies per year in the disease and NAFLD. Insulin resistance, a well estab- United States. The vast majority of gallstones (more lished key event in the development and progres- than 75%) are of cholesterol or cholesterol-predom- sion of NAFLD, has also been shown to cause inant type. In this issue of Current Opinion in cholesterol gallstone formation. In addition, apart Gastroenterology, Shabanzadeh reports on the epi- from common risk factors, NAFLD has been identi- demiology of gallstone disease on the basis of ultra- fied as an independent risk factor of gallstone sound screening, notably in population cohorts disease. Conversely gallstone disease and cholecys- unaware of the presence of gallstones. These studies tectomy have an impact on the development and indicate that

Journal

Current Opinion in GastroenterologyWolters Kluwer Health

Published: Mar 1, 2018

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