Cytomegalovirus encephalitis in the post-HAART era: is there a gold standard for treatment?

Cytomegalovirus encephalitis in the post-HAART era: is there a gold standard for treatment? Correspondence 533 Thirdly, Naccarato et al. [1] pointed out that, according to & Dome (MSD), Janssen-Cilag, Bristol Myers Squibb, their single-case experience, the combination of dolute- Boehringer Ingelheim, ViiVand Abbvie. C.R. declare no gravir and metformin should be avoided in elderly conflict of interest. All Authors have read and approved patients with sub-optimal renal function. However, the text. looking at their Table 1, the patient had serum creatinine concentrations ranging from 65 to 70mmol/l (0.7– Conflicts of interest 0.8 mg/L), thus hardly reflecting the presence of a There are no conflicts of interest. clinically relevant kidney dysfunction. Remarkably, three out of the 15 patients in our cohort who are more than 65 a,b c Dario Cattaneo , Chiara Resnati , Giuliano Rizzar- c,d b,c a years old and with serum creatinine concentrations dini and Cristina Gervasoni , Unit of Clinical ranging from 83 to 143mmol/l (0.9–1.63 mg/l) showed Pharmacology, ASST Fatebenefratelli Sacco University an optimal tolerability to dolutegravir with metformin Hospital, Gestione Ambulatoriale Politerapie (GAP) therapy. These results are in line with those by Masich Outpatient Clinic, ASST Fatebenefratelli Sacco, et al. [5] reporting no cases of lactic acidosis in patients Department of Infectious Diseases, ASST Fatebenefra- telli Sacco http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png AIDS Wolters Kluwer Health

Cytomegalovirus encephalitis in the post-HAART era: is there a gold standard for treatment?

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Publisher
Wolters Kluwer
Copyright
Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved.
ISSN
0269-9370
eISSN
1473-5571
D.O.I.
10.1097/QAD.0000000000001732
Publisher site
See Article on Publisher Site

Abstract

Correspondence 533 Thirdly, Naccarato et al. [1] pointed out that, according to & Dome (MSD), Janssen-Cilag, Bristol Myers Squibb, their single-case experience, the combination of dolute- Boehringer Ingelheim, ViiVand Abbvie. C.R. declare no gravir and metformin should be avoided in elderly conflict of interest. All Authors have read and approved patients with sub-optimal renal function. However, the text. looking at their Table 1, the patient had serum creatinine concentrations ranging from 65 to 70mmol/l (0.7– Conflicts of interest 0.8 mg/L), thus hardly reflecting the presence of a There are no conflicts of interest. clinically relevant kidney dysfunction. Remarkably, three out of the 15 patients in our cohort who are more than 65 a,b c Dario Cattaneo , Chiara Resnati , Giuliano Rizzar- c,d b,c a years old and with serum creatinine concentrations dini and Cristina Gervasoni , Unit of Clinical ranging from 83 to 143mmol/l (0.9–1.63 mg/l) showed Pharmacology, ASST Fatebenefratelli Sacco University an optimal tolerability to dolutegravir with metformin Hospital, Gestione Ambulatoriale Politerapie (GAP) therapy. These results are in line with those by Masich Outpatient Clinic, ASST Fatebenefratelli Sacco, et al. [5] reporting no cases of lactic acidosis in patients Department of Infectious Diseases, ASST Fatebenefra- telli Sacco

Journal

AIDSWolters Kluwer Health

Published: Feb 20, 2018

References

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