Systematic review Comorbidities of chronic heart failure – a systemic syndrome requiring cross-specialty efforts Wolfram Doehner J Cardiovasc Med 2018, 19:79 – 82 Common comorbidities include particularly kidney 10 – 12 injury, diabetes, arrhythmias, anaemia. Diabetes Keywords: comorbidities, heart failure, insulin resistance, mortality, stroke, mellitus may serve as a prime example of the interaction treatment of these comorbidities. Up to 30% of patients with heart Division of Cardiology and Metabolism, Department of Cardiology (CVK), and failure have concomitant diabetes mellitus and two-thirds Berlin-Brandenburg Center for Regenerative Therapies (BCRT), German Centre for Cardiovascular Research (DZHK) partner site Berlin, Charite of patients with heart failure have signs of impaired Universitatsmedizin Berlin, Germany glucose metabolism. In fact, the insulin resistance, the Correspondence to Wolfram Doehner, MD PhD, Division of Cardiology and underlying principle of type 2 diabetes mellitus, is as well Metabolism, Department of Cardiology (CVK), and Berlin-Brandenburg Center for an intrinsic metabolic feature of heart failure and pro- Regenerative Therapies (BCRT), German Centre for Cardiovascular Research (DZHK) partner site Berlin, Charite ´ Universita ¨ tsmedizin Berlin, Germany gresses with advancing heart failure (Fig. 2). Targeting E-mail: firstname.lastname@example.org insulin resistance, ideally even before overt diabetes mellitus may be diagnosed, could be a
Journal of Cardiovascular Medicine – Wolters Kluwer Health
Published: Mar 1, 2018
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