Changing patterns in treatment of angle closure glaucoma

Changing patterns in treatment of angle closure glaucoma Purpose of reviewAngle closure glaucoma is a leading cause of blindness globally and trends of how best to treat this disease are evolving. The advent of anterior segment imaging aids our understanding of pathogenesis and allows more robust and objective measurement of treatment modalities. We will also review recent literature regarding the role of laser and surgical interventions for the treatment of primary angle closure disease.Recent findingsRecent studies evaluating the efficacy of laser peripheral iridotomy (LPI) in primary angle closure suspects (PACs) show that while it is a safe intervention and initially anterior chamber angle widens following the laser treatment, the effect is lost with time. Only a small minority of PACs patients develop primary angle closure (PAC) or primary angle closure glaucoma (PACG). Trials evaluating argon laser peripheral iridoplasty (ALPI) have failed to show a substantial clinical benefit. In patients with early or moderate PACG and those with PAC with IOP over 30 mmHg, clear lens extraction is associated with better clinical and quality of life outcomes than LPI.SummaryRecent evidence supports initial clear lens extraction in the context of PACG or primary angle closure with IOP more than 30 mmHg. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Opinion in Ophthalmology Wolters Kluwer Health

Changing patterns in treatment of angle closure glaucoma

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Publisher
Wolters Kluwer
Copyright
Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved.
ISSN
1040-8738
eISSN
1531-7021
D.O.I.
10.1097/ICU.0000000000000453
Publisher site
See Article on Publisher Site

Abstract

Purpose of reviewAngle closure glaucoma is a leading cause of blindness globally and trends of how best to treat this disease are evolving. The advent of anterior segment imaging aids our understanding of pathogenesis and allows more robust and objective measurement of treatment modalities. We will also review recent literature regarding the role of laser and surgical interventions for the treatment of primary angle closure disease.Recent findingsRecent studies evaluating the efficacy of laser peripheral iridotomy (LPI) in primary angle closure suspects (PACs) show that while it is a safe intervention and initially anterior chamber angle widens following the laser treatment, the effect is lost with time. Only a small minority of PACs patients develop primary angle closure (PAC) or primary angle closure glaucoma (PACG). Trials evaluating argon laser peripheral iridoplasty (ALPI) have failed to show a substantial clinical benefit. In patients with early or moderate PACG and those with PAC with IOP over 30 mmHg, clear lens extraction is associated with better clinical and quality of life outcomes than LPI.SummaryRecent evidence supports initial clear lens extraction in the context of PACG or primary angle closure with IOP more than 30 mmHg.

Journal

Current Opinion in OphthalmologyWolters Kluwer Health

Published: Mar 1, 2018

References

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