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ORIGINAL ARTICLE Utility of Contrast-Enhanced FDG-PET/CT in the Clinical Management of Pancreatic Cancer Impact on Diagnosis, Staging, Evaluation of Treatment Response, and Detection of Recurrence Akinori Asagi, MD,* Koji Ohta, MD, PhD,Þ Junichirou Nasu, MD, PhD,* Minoru Tanada, MD,Þ Seijin Nadano, MD,* Rieko Nishimura, MD, PhD,þ Norihiro Teramoto, MD, PhD,þ Kazuhide Yamamoto, MD, PhD,§ Takeshi Inoue, MD, PhD,|| and Haruo Iguchi, MD, PhD* of patients with pancreatic cancer was almost equal to the Objectives: Fluorodeoxyglucose (FDG)Ypositron emission tomogra- number of pancreatic cancerYrelated deaths. However, a slight phy/contrast-enhanced computed tomography (PET/CE-CT) involving improvement in survival has been observed with the introduc- whole-body scanning first by nonYCE-CT and FDG-PET followed by tion of gemcitabine and S-1 as chemotherapeutic medications 3,4 CE-CT has been used for detailed examination of pancreatic lesions. We for pancreatic cancer. Given this situation, clinical practice evaluated PET/CE-CT images with regard to differential diagnosis, stag- guidelines for pancreatic cancer have recently been established ing, treatment response, and postoperative recurrence in pancreatic cancer. in Japan, and treatment regimens are determined on the basis of Methods: Positron emission tomography/CE-CTwas conducted in 108 the extent of pancreatic cancer, which is evaluated by imaging. patients with pancreatic cancer and in 41 patients
Pancreas – Wolters Kluwer Health
Published: Jan 1, 2013
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