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Unresolved Problems in the Diet‐Heart Issue

Unresolved Problems in the Diet‐Heart Issue Review Unresolved Problems in the Diet-Heart Issue Henry C. McGill, Jr., C. Alex McMahan, and Jamie Dollahlte Wene n enigma for the 1980s is the continuing diet- heart controversy. Over 60 years ago, the The Problem of Correlations cholesterol-fed rabbit model of atherosclerosis Associations Based on Group Values was discovered, and coronary atherosclerosis Associations Based on Individual Values was linked to the clinical syndrome of myocar- Effect of Within-Subject Variation on Group dial infarction. Over 30 years ago, the role of Correlation dietary fat in the etiology of atherosclerotic Some Examples disease was suggested, and epidemiologic Evaluation of Group and Individual Correla- evidence linking diet to atherosclerotic disease tions began to accumulate. The number of scientific Response of High Density Upoprotein Choles- papers on diet and atherosclerosis is now terol to Dietary Factors enormous. On the one hand, believers assemble these reports into an argument for dietary Adaptation to Diet cholesterol and saturated fat being major Conclusion causative agents for the high levels of atheroscle- rosis in the technically developed countries. On the other hand, skeptics contend that inconsis- tencies, gaps, and paradoxes in the evidence do not permit one to infer a causative relationship apparent contradiction between correlation http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Arteriosclerosis Wolters Kluwer Health

Unresolved Problems in the Diet‐Heart Issue

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Copyright
© 1981 by American Heart Association, Inc.
ISSN
0276-5047

Abstract

Review Unresolved Problems in the Diet-Heart Issue Henry C. McGill, Jr., C. Alex McMahan, and Jamie Dollahlte Wene n enigma for the 1980s is the continuing diet- heart controversy. Over 60 years ago, the The Problem of Correlations cholesterol-fed rabbit model of atherosclerosis Associations Based on Group Values was discovered, and coronary atherosclerosis Associations Based on Individual Values was linked to the clinical syndrome of myocar- Effect of Within-Subject Variation on Group dial infarction. Over 30 years ago, the role of Correlation dietary fat in the etiology of atherosclerotic Some Examples disease was suggested, and epidemiologic Evaluation of Group and Individual Correla- evidence linking diet to atherosclerotic disease tions began to accumulate. The number of scientific Response of High Density Upoprotein Choles- papers on diet and atherosclerosis is now terol to Dietary Factors enormous. On the one hand, believers assemble these reports into an argument for dietary Adaptation to Diet cholesterol and saturated fat being major Conclusion causative agents for the high levels of atheroscle- rosis in the technically developed countries. On the other hand, skeptics contend that inconsis- tencies, gaps, and paradoxes in the evidence do not permit one to infer a causative relationship apparent contradiction between correlation

Journal

ArteriosclerosisWolters Kluwer Health

Published: May 1, 1981

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