Access the full text.
Sign up today, get DeepDyve free for 14 days.
S. Harris, N. Watts, H. Genant, C. McKeever, T. Hangartner, Michael Keller, C. Chesnut, Jacques Brown, E. Eriksen, M. Hoseyni, D. Axelrod, P. Miller (1999)
Effects of risedronate treatment on vertebral and nonvertebral fractures in women with postmenopausal osteoporosis: a randomized controlled trial. Vertebral Efficacy With Risedronate Therapy (VERT) Study Group.JAMA, 282 14
(2007)
Fixed effects vs. random effects. In: Introduction to Meta-analysis
Zhao Chen, M. Maricic, M. Pettinger, C. Ritenbaugh, A. Lopez, D. Barad, M. Gass, M. LeBoff, T. Bassford (2005)
Osteoporosis and rate of bone loss among postmenopausal survivors of breast cancerCancer, 104
Donatella Bonaiuti, B. Shea, R. Iovine, Stefano Negrini, Vivian Welch, Han Kemper, George Wells, P. Tugwell, A. Cranney (2002)
Exercise for preventing and treating osteoporosis in postmenopausal women.The Cochrane database of systematic reviews, 3
Matthew Strope, Peggy Nigh, Melissa Carter, N. Lin, Jun Jiang, P. Hinton (2015)
Physical Activity–Associated Bone Loading During Adolescence and Young Adulthood Is Positively Associated With Adult Bone Mineral Density in MenAmerican Journal of Men's Health, 9
G. Gross, C. Ott, A. Lindsey, J. Twiss, N. Waltman (2002)
Postmenopausal breast cancer survivors at risk for osteoporosis: physical activity, vigor, and vitality.Oncology nursing forum, 29 9
L. Lanyon (1996)
Using functional loading to influence bone mass and architecture: objectives, mechanisms, and relationship with estrogen of the mechanically adaptive process in bone.Bone, 18 1 Suppl
E. McCloskey, A. Odén, N. Harvey, W. Leslie, D. Hans, H. Johansson, R. Barkmann, S. Boutroy, Jacques Brown, R. Chapurlat, P. Elders, Y. Fujita, C. Glüer, D. Goltzman, M. Iki, M. Karlsson, A. Kindmark, M. Kotowicz, N. Kurumatani, T. Kwok, O. Lamy, J. Leung, K. Lippuner, Ö. Ljunggren, M. Lorentzon, D. Mellström, T. Merlijn, L. Oei, C. Ohlsson, J. Pasco, F. Rivadeneira, B. Rosengren, E. Sornay‐Rendu, P. Szulc, J. Tamaki, J. Kanis (2016)
A Meta‐Analysis of Trabecular Bone Score in Fracture Risk Prediction and Its Relationship to FRAXJournal of Bone and Mineral Research, 31
Laskey (1996)
Dual-energy X-ray absorptiometry and body compositionNutrition, 12
L. Peppone, K. Mustian, R. Rosier, J. Carroll, J. Purnell, M. Janelsins, G. Morrow, S. Mohile (2013)
Bone health issues in breast cancer survivors: a Medicare Current Beneficiary Survey (MCBS) studySupportive Care in Cancer, 22
N. Morton (2009)
The PEDro scale is a valid measure of the methodological quality of clinical trials: a demographic study.The Australian journal of physiotherapy, 55 2
D. Moher, A. Liberati, J. Tetzlaff, D. Altman (2009)
Preferred reporting items for systematic reviews and meta-analyses: the PRISMA StatementOpen Medicine, 3
R. Love, G. Young, A. Laudico, N. Dinh, Gemma Uy, L. Quang, A. Peña, R. Dofitas, Orlino Bisquera, S. Siguan, Jonathan Salvador, Maria Mirasol-Lumague, N. Navarro, N. Linh, D. Jarjoura (2013)
Bone mineral density following surgical oophorectomy and tamoxifen adjuvant therapy for breast cancerCancer, 119
G. Kelley, K. Kelley, W. Kohrt (2013)
Exercise and Bone Mineral Density in Premenopausal Women: A Meta-Analysis of Randomized Controlled TrialsInternational Journal of Endocrinology, 2013
B. Hillner, J. Ingle, R. Chlebowski, J. Gralow, G. Yee, N. Janjan, J. Cauley, B. Blumenstein, K. Albain, A. Lipton, Susan Brown (2003)
American Society of Clinical Oncology 2003 update on the role of bisphosphonates and bone health issues in women with breast cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 21 21
A. McLendon, C. Woodis (2014)
A Review of Osteoporosis Management in Younger Premenopausal WomenWomen's Health, 10
L. Hedges (1989)
A Practical Guide to Modern Methods of Meta-Analysis.
H. Almstedt, Heather Tarleton (2015)
Mind the gaps: missed opportunities to promote bone health among cancer survivorsSupportive Care in Cancer, 23
G. Blake, I. Fogelman (2009)
The clinical role of dual energy X-ray absorptiometry.European journal of radiology, 71 3
Moher (2009)
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: the PRISMA statementPLoS Med, 6
K. Winters-Stone, J. Dobek, L. Nail, Jill Bennett, M. Leo, A. Naik, A. Schwartz (2011)
Strength training stops bone loss and builds muscle in postmenopausal breast cancer survivors: a randomized, controlled trialBreast Cancer Research and Treatment, 127
C. Maher, C. Sherrington, R. Herbert, A. Moseley, M. Elkins (2003)
Reliability of the PEDro scale for rating quality of randomized controlled trials.Physical therapy, 83 8
T. Tonezzer, C. Pereira, U. Filho, A. Marx (2010)
Hormone therapy/adjuvant chemotherapy induced deleterious effects on the bone mass of breast cancer patients and the intervention of physiotherapy: a literature review.European journal of gynaecological oncology, 31 3
J. Espinosa (2004)
Comprehensive Meta-Analysis, 2
(2016)
Unauthorized reproduction of this article is prohibited
(2009)
The PRISMA Group. Preferred Reporting Items for Systematic Reviews and MetaAnalyses: the PRISMA statement
Soo Kim, Y. Cho, Sei-Joong Kim, S. Hong, M. Han, Eunju Choi (2016)
The Effect on Bone Outcomes of Adding Exercise to Supplements for Osteopenic Breast Cancer Survivors: A Pilot Randomized Controlled TrialCancer Nursing, 39
A. Gómez-Cabello, Ignacio Ara, Ignacio Ara, A. González-Agüero, J. Casajús, G. Vicente-Rodríguez (2012)
Effects of Training on Bone Mass in Older AdultsSports Medicine, 42
Megan Kenyon, D. Mayer, A. Owens (2014)
Late and long-term effects of breast cancer treatment and surveillance management for the general practitioner.Journal of obstetric, gynecologic, and neonatal nursing : JOGNN, 43 3
Chun (2011)
Bone densitometrySemin Nucl Med, 41
Kelley (1998)
Exercise and regional bone mineral density in postmenopausal women: a meta-analytic review of randomized trialsAm J Phys Med Rehabil, 77
P. Hadji (2015)
Cancer Treatment-Induced Bone Loss in women with breast cancer.BoneKEy reports, 4
Kerri Winters-Stone, Jessica Dobek, L. Nail, Jill Bennett, Michael Leo, B. Torgrimson-Ojerio, S. Luoh, Anna Schwartz (2013)
Impact + resistance training improves bone health and body composition in prematurely menopausal breast cancer survivors: a randomized controlled trialOsteoporosis International, 24
K. Winters-Stone, A. Schwartz, S. Hayes, C. Fabian, K. Campbell (2012)
A prospective model of care for breast cancer rehabilitation: Bone health and arthralgiasCancer, 118
(1996)
Dual-energy X-ray absorptiometry and body composition. Nutrition
(2014)
Cancer Treatment and Survivorship Facts & Figures
D. Reid (2009)
Prevention of osteoporosis after breast cancer.Maturitas, 64 1
K. Winters-Stone, M. Laudermilk, Kaitlin Woo, Justin Brown, K. Schmitz (2014)
Influence of weight training on skeletal health of breast cancer survivors with or at risk for breast cancer-related lymphedemaJournal of Cancer Survivorship, 8
T. Saarto, H. Sievänen, P. Kellokumpu-Lehtinen, R. Nikander, L. Vehmanen, R. Huovinen, Hannu Kautiainen, S. Järvenpää, H. Penttinen, M. Utriainen, Anna-Stina Jääskeläinen, Anneli Elme, Johanna Ruohola, T. Palva, Harri Vertio, Matti Rautalahti, Mikael Fogelholm, R. Luoto, Carl Blomqvist (2012)
Effect of supervised and home exercise training on bone mineral density among breast cancer patients. A 12-month randomised controlled trialOsteoporosis International, 23
A. Cranney, V. Welch, G. Wells, J. Adachi, B. Shea, L. Simon, P. Tugwell (2001)
Discrimination of changes in osteoporosis outcomes.The Journal of rheumatology, 28 2
K. Winters-Stone, A. Schwartz, L. Nail (2010)
A review of exercise interventions to improve bone health in adult cancer survivorsJournal of Cancer Survivorship, 4
J. Matthews, D. Altman (1996)
Statistics notes: Interaction 3: How to examine heterogeneityBMJ, 313
R. Mazess (1986)
Bone densitometry.British Medical Journal (Clinical research ed.), 293
M. Irwin, Marty Alvarez-Reeves, Lisa Cadmus, Eileen Mierzejewski, S. Mayne, Herbert Yu, G. Chung, B. Jones, M. Knobf, L. DiPietro (2009)
Exercise Improves Body Fat, Lean Mass, and Bone Mass in Breast Cancer SurvivorsObesity, 17
L. Plank (2005)
Dual-energy X-ray absorptiometry and body compositionCurrent Opinion in Clinical Nutrition and Metabolic Care, 8
G. Kelley (1998)
Exercise and regional bone mineral density in postmenopausal women: a meta-analytic review of randomized trials.American journal of physical medicine & rehabilitation, 77 1
Purpose: The purpose of this systematic review and meta-analysis was to synthesize the current literature on the effects of bone-loading exercise on bone mineral density (BMD) in women after treatment of breast cancer (BC). Methods: PubMed, Cumulative Index to Nursing and Allied Health Literature (CINAHL), Physiotherapy Evidence Database (PEDro), and Web of Science databases were searched through March 31, 2016. A combination of MeSH terms and key words was used: (physical therapy OR physiotherapy OR resistance training OR weight training OR aerobic OR exercise) AND (bone density OR osteoporosis) AND breast cancer. Search terms for PEDro were as follows: (breast cancer AND bone breast cancer) and (breast cancer AND osteoporosis). Studies included were experimental studies that compared any type of bone-loading exercise intervention with a comparison group and reported dual-energy x-ray absorptiometry for assessment of BMD of the lumbar spine and/or proximal femur (femoral neck, trochanter, and/or total hip). Between-group BMD effect sizes and 95% confidence intervals (CIs) were calculated for each study (bone-loading exercise vs usual care/non–bone-loading exercise) and pooled across studies. Risk of bias in and across studies was addressed using the PEDro scale. Results: Five randomized controlled studies were included. Pooled effect sizes were statistically significant, favoring the bone-loading exercise group for proximal femur (d = 0.15; 95% CI, 0.03-0.28) and for lumbar spine BMD (d = 0.14; 95% CI, 0.01-0.27). Conclusion: Results provide modest evidence that bone-loading exercise interventions have statistically and clinically significant effects on proximal femur and lumbar spine BMD in women treated for BC. Further research is warranted to determine the most effective types and intensities of exercise for improving BMD in BC survivors.
Rehabilitation Oncology – Wolters Kluwer Health
Published: Oct 1, 2016
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.