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SSRIs: An Update for Home Care Clinicians

SSRIs: An Update for Home Care Clinicians Downloaded from http://journals.lww.com/homehealthcarenurseonline by BhDMf5ePHKbH4TTImqenVJ2toCr/9wZZjwPUWvYES9l2nY+zyylnl33NGMK6MRsx on 10/24/2020 1.5 HOURS Continuing Education SSRIs: An Update for Home Care Clinicians ne out of seven community-dwelling older (Salehi et al., 2019). We do know that SSRIs act by adults is prescribed an antidepressant targeting and inhibiting serotonin transporter, drug (Gebara et al., 2015). Nationally, anti- which inhibits serotonin reuptake, thereby increas- depressant use increased by almost 65% ing the availability of serotonin to receptors in in recent decades (Pratt et al., 2017), and approxi- synapses (Garfield et al., 2014; Salehi et al.). mately 5% of the 17 million adults receiving anti- depressant treatment are over age 50 (National Side Effects and Adverse Events Institute of Mental Health, 2019). As people age, Central and peripheral serotonin receptors are they experience changes in pharmacokinetics affected when SSRIs inhibit serotonin transporter, (how the body absorbs, distributes, metabolizes, potentially resulting in both central and periph- and eliminates drugs), and pharmacodynamics eral nervous system side effects. Although SSRIs (the drug’s effect on the body), creating higher are associated with fewer side effects than other risk for adverse drug effects. Thus, a cautious ap- antidepressants, nearly 40% of those taking SSRIs proach to prescribing antidepressant medications report experiencing http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Home Healthcare Now Wolters Kluwer Health

SSRIs: An Update for Home Care Clinicians

Home Healthcare Now , Volume 38 (5) – Oct 1, 2020

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References (21)

Publisher
Wolters Kluwer Health
Copyright
Wolters Kluwer Health, Inc. All rights reserved.
ISSN
2374-4529
eISSN
2374-4537
DOI
10.1097/NHH.0000000000000897
Publisher site
See Article on Publisher Site

Abstract

Downloaded from http://journals.lww.com/homehealthcarenurseonline by BhDMf5ePHKbH4TTImqenVJ2toCr/9wZZjwPUWvYES9l2nY+zyylnl33NGMK6MRsx on 10/24/2020 1.5 HOURS Continuing Education SSRIs: An Update for Home Care Clinicians ne out of seven community-dwelling older (Salehi et al., 2019). We do know that SSRIs act by adults is prescribed an antidepressant targeting and inhibiting serotonin transporter, drug (Gebara et al., 2015). Nationally, anti- which inhibits serotonin reuptake, thereby increas- depressant use increased by almost 65% ing the availability of serotonin to receptors in in recent decades (Pratt et al., 2017), and approxi- synapses (Garfield et al., 2014; Salehi et al.). mately 5% of the 17 million adults receiving anti- depressant treatment are over age 50 (National Side Effects and Adverse Events Institute of Mental Health, 2019). As people age, Central and peripheral serotonin receptors are they experience changes in pharmacokinetics affected when SSRIs inhibit serotonin transporter, (how the body absorbs, distributes, metabolizes, potentially resulting in both central and periph- and eliminates drugs), and pharmacodynamics eral nervous system side effects. Although SSRIs (the drug’s effect on the body), creating higher are associated with fewer side effects than other risk for adverse drug effects. Thus, a cautious ap- antidepressants, nearly 40% of those taking SSRIs proach to prescribing antidepressant medications report experiencing

Journal

Home Healthcare NowWolters Kluwer Health

Published: Oct 1, 2020

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