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Review of Ongoing Clinical Trials in Non–Small-Cell Lung Cancer A Status Report for 2012 from the ClinicalTrials.gov

Review of Ongoing Clinical Trials in Non–Small-Cell Lung Cancer A Status Report for 2012... STATE OF THE ART: CONCISE REvIEW Review of Ongoing Clinical Trials in Non–Small-Cell  Lung Cancer A Status Report for 2012 from the ClinicalTrials.gov Web Site Janakiraman Subramanian, MD, MPH,* Thomas Regenbogen, MB BCh BAO,† Gayathri Nagaraj, MD,‡ Alex Lane, BS,§ Siddhartha Devarakonda, MD,║ Gongfu Zhou, PhD,¶ and Ramaswamy Govindan, MD§# Conclusions:Our survey identified major changes in lung cancer clin- Introduction:Clinical research in non–small-cell lung cancer ical research since 2009. Almost half of all studies registered at the (NSCLC) is a rapidly evolving field. In an effort to identify the cur - ClinicalTrials.gov Web site are being conducted outside the United rent trends in lung cancer clinical research, we reviewed ongoing States, and several novel molecularly targeted agents are being evalu- clinical trials in NSCLC listed in the ClinicalTrials.gov registry in ated in the treatment of patients with NSCLC. More importantly, we 2012, and we also compared this data to a similar survey conducted identified a threefold increase in the number of studies that perform by us in 2009. biomarker testing to determine patient selection over the last 3 years. Methods:The Web site’s advanced search function was used to search for the term “non-small cell lung cancer.” The search was Key Words: Non–small-cell lung cancer, ClinicalTrials.gov, Lung http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Thoracic Oncology Wolters Kluwer Health

Review of Ongoing Clinical Trials in Non–Small-Cell Lung Cancer A Status Report for 2012 from the ClinicalTrials.gov

Govindan, Ramaswamy
Journal of Thoracic Oncology , Volume 8 (7) – Jul 1, 2013
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Copyright
Copyright © 2013 by the International Association for the Study of Lung Cancer
ISSN
1556-0864
DOI
10.1097/JTO.0b013e318287c562
pmid
23478543
Publisher site
See Article on Publisher Site

Abstract

STATE OF THE ART: CONCISE REvIEW Review of Ongoing Clinical Trials in Non–Small-Cell  Lung Cancer A Status Report for 2012 from the ClinicalTrials.gov Web Site Janakiraman Subramanian, MD, MPH,* Thomas Regenbogen, MB BCh BAO,† Gayathri Nagaraj, MD,‡ Alex Lane, BS,§ Siddhartha Devarakonda, MD,║ Gongfu Zhou, PhD,¶ and Ramaswamy Govindan, MD§# Conclusions:Our survey identified major changes in lung cancer clin- Introduction:Clinical research in non–small-cell lung cancer ical research since 2009. Almost half of all studies registered at the (NSCLC) is a rapidly evolving field. In an effort to identify the cur - ClinicalTrials.gov Web site are being conducted outside the United rent trends in lung cancer clinical research, we reviewed ongoing States, and several novel molecularly targeted agents are being evalu- clinical trials in NSCLC listed in the ClinicalTrials.gov registry in ated in the treatment of patients with NSCLC. More importantly, we 2012, and we also compared this data to a similar survey conducted identified a threefold increase in the number of studies that perform by us in 2009. biomarker testing to determine patient selection over the last 3 years. Methods:The Web site’s advanced search function was used to search for the term “non-small cell lung cancer.” The search was Key Words: Non–small-cell lung cancer, ClinicalTrials.gov, Lung

Journal

Journal of Thoracic Oncology – Wolters Kluwer Health

Published: Jul 1, 2013

References

  • Cancer statistics, 2012
    Siegel