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Respiratory Physiology

Respiratory Physiology Respiratory Physiology: Gas Exchange and Respiratory Mechanics Luca M. Bigatello, MD Department of Anesthesia and Critical Care VA Boston Healthcare System Massachusetts General Hospital Harvard Medical School Boston, Massachusetts espiration provides oxygen (O ) and removes Hence, with a normal PaCO of 40 mm Hg, the alveolar 2 2 carbon dioxide (CO ) from the body. An extra- PO (PAO ) will be: 2 2 2 Rordinary anatomic arrangement of functional units (the alveoli) bordered by extra-thin walls (epithelium PAO ¼ PiO  PaCO  1:2  100mmHg: 2 2 2 and endothelium) creates the interface for gas exchange between blood and air. Repetitive expansion of the chest facilitates movement of gas in and out of the lungs. The Past the pulmonary capillaries, the arterial blood re- proper function of respiration includes further complex- ceives a small amount of nonoxygenated blood, for ex- ities, such as the control of breathing, neuromuscular ample, from the bronchial circulation, and the PaO activity, and the interplay of endocrine and metabolic decreases slightly below 100 mm Hg. factors. In this review, we will focus our discussion on gas exchange and respiratory mechanics. Causes of Hypoxemia Understanding how O moves from the air to http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png ASA Refresher Courses in Anesthesiology Wolters Kluwer Health

Respiratory Physiology

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Copyright
Copyright © 2010 The American Society of Anesthesiologists, Inc.
ISSN
0363-471X
DOI
10.1097/ASA.0b013e3181fe954c
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Abstract

Respiratory Physiology: Gas Exchange and Respiratory Mechanics Luca M. Bigatello, MD Department of Anesthesia and Critical Care VA Boston Healthcare System Massachusetts General Hospital Harvard Medical School Boston, Massachusetts espiration provides oxygen (O ) and removes Hence, with a normal PaCO of 40 mm Hg, the alveolar 2 2 carbon dioxide (CO ) from the body. An extra- PO (PAO ) will be: 2 2 2 Rordinary anatomic arrangement of functional units (the alveoli) bordered by extra-thin walls (epithelium PAO ¼ PiO  PaCO  1:2  100mmHg: 2 2 2 and endothelium) creates the interface for gas exchange between blood and air. Repetitive expansion of the chest facilitates movement of gas in and out of the lungs. The Past the pulmonary capillaries, the arterial blood re- proper function of respiration includes further complex- ceives a small amount of nonoxygenated blood, for ex- ities, such as the control of breathing, neuromuscular ample, from the bronchial circulation, and the PaO activity, and the interplay of endocrine and metabolic decreases slightly below 100 mm Hg. factors. In this review, we will focus our discussion on gas exchange and respiratory mechanics. Causes of Hypoxemia Understanding how O moves from the air to

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ASA Refresher Courses in Anesthesiology – Wolters Kluwer Health

Published: Jan 1, 2010

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