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Neuroendocrine tumors of the diffuse neuroendocrine system

Neuroendocrine tumors of the diffuse neuroendocrine system a,b,c a a Bjo ¨ rn I. Gustafsson , Mark Kidd and Irvin M. Modlin Department of Surgery, Yale University School of Purpose of review Medicine, New Haven, Connecticut, USA, Department Neuroendocrine tumors (previously referred to as carcinoids) are ill-understood, of Gastroenterology, St Olavs Hospital HF, Trondheim University Hospital and Department of Cancer enigmatic malignancies that, although slow-growing compared with adenocarcinomas, Research and Molecular Medicine, Faculty of Medicine, can behave aggressively. In 2004, they comprised 1.25% of all malignancies; their Norwegian University of Science and Technology, Trondheim, Norway incidence is increasing by approximately 6% per year. The present review provides an overview on neuroendocrine tumors and focuses on general features and current Correspondence to Irvin M. Modlin, MD, PhD, DSc, FRCS (Ed, Eng), Department of Gastroenterological diagnostic and therapeutic options. Surgery, Yale University School of Medicine, 333 Recent findings Cedar Street, P.O. Box 208062, New Haven, CT 06520-8062, USA Neuroendocrine tumors may present a considerable diagnostic and therapeutic Tel: +1 203 785 5429; fax: +1 203 737 4067; challenge as their clinical presentation is nonspecific and usually late, when metastases e-mail: [email protected] are already evident. Topographic localization is by computed tomography, magnetic resonance imaging, somatostatin receptor scintigraphy, whole-body positron http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Opinion in Oncology Wolters Kluwer Health

Neuroendocrine tumors of the diffuse neuroendocrine system

Modlin, Irvin M
Current Opinion in Oncology , Volume 20 (1) – Jan 1, 2008
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ISSN
1040-8746
eISSN
1531-703X
DOI
10.1097/CCO.0b013e3282f1c595
pmid
18043250
Publisher site
See Article on Publisher Site

Abstract

a,b,c a a Bjo ¨ rn I. Gustafsson , Mark Kidd and Irvin M. Modlin Department of Surgery, Yale University School of Purpose of review Medicine, New Haven, Connecticut, USA, Department Neuroendocrine tumors (previously referred to as carcinoids) are ill-understood, of Gastroenterology, St Olavs Hospital HF, Trondheim University Hospital and Department of Cancer enigmatic malignancies that, although slow-growing compared with adenocarcinomas, Research and Molecular Medicine, Faculty of Medicine, can behave aggressively. In 2004, they comprised 1.25% of all malignancies; their Norwegian University of Science and Technology, Trondheim, Norway incidence is increasing by approximately 6% per year. The present review provides an overview on neuroendocrine tumors and focuses on general features and current Correspondence to Irvin M. Modlin, MD, PhD, DSc, FRCS (Ed, Eng), Department of Gastroenterological diagnostic and therapeutic options. Surgery, Yale University School of Medicine, 333 Recent findings Cedar Street, P.O. Box 208062, New Haven, CT 06520-8062, USA Neuroendocrine tumors may present a considerable diagnostic and therapeutic Tel: +1 203 785 5429; fax: +1 203 737 4067; challenge as their clinical presentation is nonspecific and usually late, when metastases e-mail: [email protected] are already evident. Topographic localization is by computed tomography, magnetic resonance imaging, somatostatin receptor scintigraphy, whole-body positron

Journal

Current Opinion in Oncology – Wolters Kluwer Health

Published: Jan 1, 2008

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