Indications for examination of spontaneous abortion specimens: A reassessment

Indications for examination of spontaneous abortion specimens: A reassessment The clinical of recurrent pregnancy loss is assessed in light of recent technical advances in trophoblast culture, ultrasonography, and chromosome analysis. With an algorithm based on karyotype results, cost-benefit calculations confirm that an average savings of $1099.47 per patient could be achieved if a policy of karyotype analysis of recurrent abortion specimens was emphasized. It is estimated that a specific chromosomal cause could be identified in 45% to 70% of such cases. A more concerted effort should be made to culture trophoblast tissue from recurrent pregnancy losses; such a policy would result in both emotional and financial rewards. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Obstetrics and Gynecology Wolters Kluwer Health

Indications for examination of spontaneous abortion specimens: A reassessment

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Publisher
Wolters Kluwer Health
Copyright
Copyright © 1995 Elsevier Ltd
ISSN
0002-9378
DOI
10.1016/0002-9378(95)90616-9
Publisher site
See Article on Publisher Site

Abstract

The clinical of recurrent pregnancy loss is assessed in light of recent technical advances in trophoblast culture, ultrasonography, and chromosome analysis. With an algorithm based on karyotype results, cost-benefit calculations confirm that an average savings of $1099.47 per patient could be achieved if a policy of karyotype analysis of recurrent abortion specimens was emphasized. It is estimated that a specific chromosomal cause could be identified in 45% to 70% of such cases. A more concerted effort should be made to culture trophoblast tissue from recurrent pregnancy losses; such a policy would result in both emotional and financial rewards.

Journal

American Journal of Obstetrics and GynecologyWolters Kluwer Health

Published: Nov 1, 1995

References

  • Chromosome analysis in spontaneous pregnancy loss: use of placental villus mesodermal core cell cultures
    Songster, GS; Sun, L; Chang, SC; Sheung, SW

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