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Fluorodeoxyglucose Uptake Measured by Positron Emission Tomography and Standardized Uptake Value Predicts Long-Term Survival of CT Screening Detected Lung Cancer in Heavy Smokers

Fluorodeoxyglucose Uptake Measured by Positron Emission Tomography and Standardized Uptake Value... ORIGINAL ARTICLE Fluorodeoxyglucose Uptake Measured by Positron Emission Tomography and Standardized Uptake Value Predicts Long-Term Survival of CT Screening Detected Lung Cancer in Heavy Smokers Ugo Pastorino, MD,* Claudio Landoni, MD,† Alfonso Marchiano`, MD,‡ Elisa Calabro`, MD,* Gabriella Sozzi, PhD,§ Rosalba Miceli, PhD, Maria Picchio, MD,† Luigi Mariani, PhD, Cristina Messa, MD,† and Ferruccio Fazio, MD† ung cancer causes over 1.3 millions annual deaths world- Background: Fluorodeoxyglucose-positron emission tomography Lwide. The overall survival of all detected lung cancers is (FDG-PET) has proven its value in the diagnosis of undetermined 2,3 15% in the United States and 10% in Europe. pulmonary lesions, lung cancer staging, and assessment of progno- In the last decade, nonrandomized trials on spiral com- sis. Purpose of this study is to clarify whether standardized uptake puted tomography (CT) screening have provided conflicting value (SUV) can predict clinical outcome of computed tomography results, where the higher proportion of CT detected stage I (CT) screening detected lung cancer. lung cancer and 90% estimated long-term survival, was Methods: We tested the predictive value of FDG-PET using SUV counterbalanced by a more than threefold excess of lung on long-term survival of 34 lung cancer patients, detected from 1035 cancer diagnosis http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Thoracic Oncology Wolters Kluwer Health

Fluorodeoxyglucose Uptake Measured by Positron Emission Tomography and Standardized Uptake Value Predicts Long-Term Survival of CT Screening Detected Lung Cancer in Heavy Smokers

Fazio, Ferruccio
Journal of Thoracic Oncology , Volume 4 (11) – Nov 1, 2009
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References (33)

ISSN
1556-0864
DOI
10.1097/JTO.0b013e3181bbf1dc
pmid
19861905
Publisher site
See Article on Publisher Site

Abstract

ORIGINAL ARTICLE Fluorodeoxyglucose Uptake Measured by Positron Emission Tomography and Standardized Uptake Value Predicts Long-Term Survival of CT Screening Detected Lung Cancer in Heavy Smokers Ugo Pastorino, MD,* Claudio Landoni, MD,† Alfonso Marchiano`, MD,‡ Elisa Calabro`, MD,* Gabriella Sozzi, PhD,§ Rosalba Miceli, PhD, Maria Picchio, MD,† Luigi Mariani, PhD, Cristina Messa, MD,† and Ferruccio Fazio, MD† ung cancer causes over 1.3 millions annual deaths world- Background: Fluorodeoxyglucose-positron emission tomography Lwide. The overall survival of all detected lung cancers is (FDG-PET) has proven its value in the diagnosis of undetermined 2,3 15% in the United States and 10% in Europe. pulmonary lesions, lung cancer staging, and assessment of progno- In the last decade, nonrandomized trials on spiral com- sis. Purpose of this study is to clarify whether standardized uptake puted tomography (CT) screening have provided conflicting value (SUV) can predict clinical outcome of computed tomography results, where the higher proportion of CT detected stage I (CT) screening detected lung cancer. lung cancer and 90% estimated long-term survival, was Methods: We tested the predictive value of FDG-PET using SUV counterbalanced by a more than threefold excess of lung on long-term survival of 34 lung cancer patients, detected from 1035 cancer diagnosis

Journal

Journal of Thoracic Oncology – Wolters Kluwer Health

Published: Nov 1, 2009

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