Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Efficacy of Inspiratory Muscle Training on Respiratory Muscle Strength in Hematopoietic Stem Cell Recipients: A Systematic Review and Meta-analysis

Efficacy of Inspiratory Muscle Training on Respiratory Muscle Strength in Hematopoietic Stem Cell... Objective: To investigate whether inspiratory muscle training improves respiratory muscle strength and function and reduces dyspnea and fatigue in hematopoietic stem cell recipients. Design: A systematic review and meta-analysis of randomized controlled trials. Participants: People with hematological neoplasms who underwent hematopoietic stem cell transplantation. Intervention: Inspiratory muscle training with POWER breath Plus, POWERbreathe, Classic, and Threshold devices, with a load of 40% of the maximum inspiratory pressure. Outcome Measures: The primary outcomes were maximal inspiratory pressure, maximal expiratory pressure, forced expiratory volume in the first second of expiration (FEV1), forced vital capacity (FVC), and the FEV1/FVC ratio. Secondary outcomes were dyspnea, fatigue, respiratory rate, peripheral O2 saturation, quality of life, and functional capacity. Results: The search identified 3 eligible studies with a sample of 108 participants. Maximal inspiratory pressure was higher in the intervention group in the 3 studies reviewed, with an average difference of −9.3 cm H2O, −31.94 cm H2O, and −16 cm H2O in relation to the control group after inspiratory muscle training. One study found an improvement in the distance covered in the 6-minute walk test (34.22 m) and in the distance covered in the modified incremental shuttle walking test (66.43 m) in the intervention group. Limitation: This systematic review includes only 3 randomized controlled clinical trials. Conclusion: Inspiratory muscle training is effective in increasing inspiratory muscle strength and functional capacity in bone marrow transplant recipients. However, its effects on fatigue and dyspnea remain uncertain. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Rehabilitation Oncology Wolters Kluwer Health

Efficacy of Inspiratory Muscle Training on Respiratory Muscle Strength in Hematopoietic Stem Cell Recipients: A Systematic Review and Meta-analysis

Download PDF
9 pages

Loading next page...
 
/lp/wolters-kluwer-health/efficacy-of-inspiratory-muscle-training-on-respiratory-muscle-strength-ORte9zz03J

References

References for this paper are not available at this time. We will be adding them shortly, thank you for your patience.

Publisher
Wolters Kluwer Health
Copyright
© 2022 Academy of Oncologic Physical Therapy, APTA.
ISSN
2168-3808
eISSN
2381-2427
DOI
10.1097/01.reo.0000000000000284
Publisher site
See Article on Publisher Site

Abstract

Objective: To investigate whether inspiratory muscle training improves respiratory muscle strength and function and reduces dyspnea and fatigue in hematopoietic stem cell recipients. Design: A systematic review and meta-analysis of randomized controlled trials. Participants: People with hematological neoplasms who underwent hematopoietic stem cell transplantation. Intervention: Inspiratory muscle training with POWER breath Plus, POWERbreathe, Classic, and Threshold devices, with a load of 40% of the maximum inspiratory pressure. Outcome Measures: The primary outcomes were maximal inspiratory pressure, maximal expiratory pressure, forced expiratory volume in the first second of expiration (FEV1), forced vital capacity (FVC), and the FEV1/FVC ratio. Secondary outcomes were dyspnea, fatigue, respiratory rate, peripheral O2 saturation, quality of life, and functional capacity. Results: The search identified 3 eligible studies with a sample of 108 participants. Maximal inspiratory pressure was higher in the intervention group in the 3 studies reviewed, with an average difference of −9.3 cm H2O, −31.94 cm H2O, and −16 cm H2O in relation to the control group after inspiratory muscle training. One study found an improvement in the distance covered in the 6-minute walk test (34.22 m) and in the distance covered in the modified incremental shuttle walking test (66.43 m) in the intervention group. Limitation: This systematic review includes only 3 randomized controlled clinical trials. Conclusion: Inspiratory muscle training is effective in increasing inspiratory muscle strength and functional capacity in bone marrow transplant recipients. However, its effects on fatigue and dyspnea remain uncertain.

Journal

Rehabilitation Oncology – Wolters Kluwer Health

Published: Jul 3, 2022

References

  • Indications for autologous and allogeneic hematopoietic cell transplantation: guidelines from the American Society for Blood and Marrow Transplantation
  • Hematopoietic stem cell transplantation
  • Quality of life in hematologic oncology patients undergoing chemotherapy
  • Cellular immunotherapy in the treatment of hematopoietic malignancies
  • Deconditioning, fatigue and impaired quality of life in long-term survivors after allogeneic hematopoietic stem cell transplantation
  • Reduced respiratory and skeletal muscle strength in survivors of sibling or unrelated donor hematopoietic stem cell transplantation
  • Idiopathic pneumonia syndrome after syngeneic bone marrow transplant in mice
  • The effect of a multimodal intervention on treatment-related symptoms in patients undergoing hematopoietic stem cell transplantation: a randomized controlled trial
  • Effects of an exercise program on muscle performance in patients undergoing allogeneic bone marrow transplantation
  • Effect of respiratory muscle training on exercise performance in healthy individuals: a systematic review and meta-analysis
  • Safety and feasibility of inspiratory muscle training for hospitalized patients undergoing hematopoietic stem cell transplantation: a randomized controlled study
  • Inspiratory muscle training in allogeneic hematopoietic stem cell transplantation recipients: a randomized controlled trial
  • Evaluation of respiratory conditions in early phase of hematopoietic stem cell transplantation
  • GRADE: an emerging consensus on rating quality of evidence and strength of recommendations
  • Cochrane handbook forsystematic reviews of interventions version 6.1. Cochrane, 2020
  • Review Manager (RevMan). Version 5.4.1. Cochrane
  • Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement
  • Reference values for the incremental shuttle walking test
  • Reference values for a multiple repetition 6-minute walk test in healthy adults older than 20 years
  • Measuring the functional impact of fatigue: initial validation of the fatigue impact scale
  • The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology
  • The structure of the Montgomery-Åsberg depression rating scale over the course of treatment for depression
  • Functional capacity change impacts the quality of life of hospitalized patients undergoing hematopoietic stem cell transplantation
  • Exercise, inflammation, and fatigue in cancer survivors
  • Cancer-related fatigue, version 2.2015