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Authors Index to Abstracts

Authors Index to Abstracts ARTERIOSCLEROSIS VOL 4, No 5, SEPTEMBER/OCTOBER 1984 568a ance liquid chromatography after initial size fractionation on Purification and Sequence Analysis of the Surface Sephadex G-50. Peptide purity was established by N-terminal Tryptic Fragments from Human Low Density Lipopro- analysis. Overall recoveries of tryptic surface peptides ranged telns from 15% to 55%. All peptides sequenced were less than ~24 H. J. Pownall, A. M. Gotto, W. A. Bradley. C.-Y. Yang, amino acids in length. Using this approach, approximately 150 Baylor College of Medicine and The Methodist Hospital, residues have been sequenced by the manual method of Chang and by gas-phase methodologies. These sequences provide use- Houston, TX ful information for the further study of the structure of human Since the handling of large fragments of human apolipoprotein apolipoprotein B. These data will be used, in part, to synthesize B remains a technically difficult problem, we have continued to oligonucleotide probes for the screening of cDNA libraries as well generate tryptic fragments from the surface of intact human low as for the production of synthetic peptides that will help Identify density lipoproteins (LDL) for characterization by sequence analy- structure-function relationships of apo B-containing lipoproteins. sis. The tryptic fragments of LDL were http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Arteriosclerosis Wolters Kluwer Health

Authors Index to Abstracts

Arteriosclerosis , Volume 4 (5) – Sep 1, 1984

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Copyright
© 1984 by American Heart Association, Inc.
ISSN
0276-5047

Abstract

ARTERIOSCLEROSIS VOL 4, No 5, SEPTEMBER/OCTOBER 1984 568a ance liquid chromatography after initial size fractionation on Purification and Sequence Analysis of the Surface Sephadex G-50. Peptide purity was established by N-terminal Tryptic Fragments from Human Low Density Lipopro- analysis. Overall recoveries of tryptic surface peptides ranged telns from 15% to 55%. All peptides sequenced were less than ~24 H. J. Pownall, A. M. Gotto, W. A. Bradley. C.-Y. Yang, amino acids in length. Using this approach, approximately 150 Baylor College of Medicine and The Methodist Hospital, residues have been sequenced by the manual method of Chang and by gas-phase methodologies. These sequences provide use- Houston, TX ful information for the further study of the structure of human Since the handling of large fragments of human apolipoprotein apolipoprotein B. These data will be used, in part, to synthesize B remains a technically difficult problem, we have continued to oligonucleotide probes for the screening of cDNA libraries as well generate tryptic fragments from the surface of intact human low as for the production of synthetic peptides that will help Identify density lipoproteins (LDL) for characterization by sequence analy- structure-function relationships of apo B-containing lipoproteins. sis. The tryptic fragments of LDL were

Journal

ArteriosclerosisWolters Kluwer Health

Published: Sep 1, 1984

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