Association between alexithymia and risk of incident cardiovascular diseases in the SUpplémentation en Vitamines et Minéraux AntioXydants (SU.VI.MAX) Cohort

Association between alexithymia and risk of incident cardiovascular diseases in the... Abstract Objective Although alexithymia has been suggested to be associated with cardiovascular diseases, studies are scarce and a causal relationship is questionable. This study explored the prospective association between alexithymia and cardiovascular events in middle-aged participants without cardiovascular history at baseline. Methods The 26-item Toronto Alexithymia Scale (TAS-26) was completed by 5,586 participants of the French Supplémentation en Vitamines et Minéraux AntioXydants (SU.VI.MAX) cohort (41.4% of men, mean age ± SD: 52.2 ± 6.3 years) in 1996-1997. Covariates measured at baseline included age, occupational status, depressive symptoms, smoking status, body mass index, hypertension, diabetes, hypercholesterolemia and hypertriglyceridemia. The follow-up ran from January 1, 1998 to the date of the first cardiovascular event, the date of death or September 1, 2007, whichever occurred first. Cardiovascular events were validated by an independent expert committee. Hazard ratios (HR) and 95% confidence intervals (CI) were computed with Cox regressions. Results During an average of 8.9 years of follow-up, 171 first cardiovascular events were validated. Adjusting for age, sex and occupational status, there was no association between baseline alexithymia and cardiovascular events at follow-up (HR [95% CI] for 15 points of TAS-26: 1.00 [0.81-1.23], p > 0.99). Adjusting for all covariates, using binary TAS-26 cut-offs or TAS-26 subscores yielded similar non-significant results. Conclusions In this large prospective study, alexithymia and cardiovascular events were not associated among a nonclinical population. This casts some doubt on whether alexithymia could be a meaningful target in the prevention of cardiovascular diseases. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Psychosomatic Medicine Wolters Kluwer Health

Association between alexithymia and risk of incident cardiovascular diseases in the SUpplémentation en Vitamines et Minéraux AntioXydants (SU.VI.MAX) Cohort

Loading next page...
 
/lp/wolters-kluwer-health/association-between-alexithymia-and-risk-of-incident-cardiovascular-haA0CXzcum
Publisher
Wolters Kluwer Health
Copyright
Copyright © 2018 by the American Psychosomatic Society
ISSN
0033-3174
eISSN
1534-7796
D.O.I.
10.1097/PSY.0000000000000592
Publisher site
See Article on Publisher Site

Abstract

Abstract Objective Although alexithymia has been suggested to be associated with cardiovascular diseases, studies are scarce and a causal relationship is questionable. This study explored the prospective association between alexithymia and cardiovascular events in middle-aged participants without cardiovascular history at baseline. Methods The 26-item Toronto Alexithymia Scale (TAS-26) was completed by 5,586 participants of the French Supplémentation en Vitamines et Minéraux AntioXydants (SU.VI.MAX) cohort (41.4% of men, mean age ± SD: 52.2 ± 6.3 years) in 1996-1997. Covariates measured at baseline included age, occupational status, depressive symptoms, smoking status, body mass index, hypertension, diabetes, hypercholesterolemia and hypertriglyceridemia. The follow-up ran from January 1, 1998 to the date of the first cardiovascular event, the date of death or September 1, 2007, whichever occurred first. Cardiovascular events were validated by an independent expert committee. Hazard ratios (HR) and 95% confidence intervals (CI) were computed with Cox regressions. Results During an average of 8.9 years of follow-up, 171 first cardiovascular events were validated. Adjusting for age, sex and occupational status, there was no association between baseline alexithymia and cardiovascular events at follow-up (HR [95% CI] for 15 points of TAS-26: 1.00 [0.81-1.23], p > 0.99). Adjusting for all covariates, using binary TAS-26 cut-offs or TAS-26 subscores yielded similar non-significant results. Conclusions In this large prospective study, alexithymia and cardiovascular events were not associated among a nonclinical population. This casts some doubt on whether alexithymia could be a meaningful target in the prevention of cardiovascular diseases.

Journal

Psychosomatic MedicineWolters Kluwer Health

Published: Nov 1, 2018

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off