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Adherence to and outcome of isoniazid chemoprophylaxis among household contact children of adults having pulmonary tuberculosis in Alexandria, Egypt

Adherence to and outcome of isoniazid chemoprophylaxis among household contact children of adults... Original article 71 Adherence to and outcome of isoniazid chemoprophylaxis among household contact children of adults having pulmonary tuberculosis in Alexandria, Egypt Aida M. Mohamed Department of Community Medicine, Faculty of Background Medicine, Alexandria University, Alexandria, Egypt Current international guidelines recommend 6–9 months of isoniazid (INH) preventive Correspondence to Aida M. Mohamed, Department of chemotherapy to prevent the development of active tuberculosis (TB) in susceptible Community Medicine, Alexandria University, children exposed to Mycobacterium tuberculosis. However, this is dependent on good Alexandria, Egypt E-mail: aida_mohey@yahoo.com adherence, as shown by previous studies. Objectives Received 3 July 2012 Accepted 4 July 2012 This study was conducted to describe the outcome of screening of contact children aged 5 years or less with household exposure to an adult pulmonary TB index case to Journal of the Egyptian Public Health Association 2012, 87:71–78 determine the prevalence and possible risk factors of infection among contact children and to determine the extent and outcome of adherence of contact children to unsupervised INH chemoprophylaxis for 6 months. Methods A descriptive facility-based cross-sectional study was conducted from March 2009 to August 2010. Research settings were three of the National TB control program chest dispensaries (primary care facilities) in Alexandria, http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of the Egyptian Public Health Association Wolters Kluwer Health

Adherence to and outcome of isoniazid chemoprophylaxis among household contact children of adults having pulmonary tuberculosis in Alexandria, Egypt

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Copyright
© 2012 Egyptian Public Health Association
ISSN
0013-2446
DOI
10.1097/01.EPX.0000417999.05730.32
pmid
22936243

Abstract

Original article 71 Adherence to and outcome of isoniazid chemoprophylaxis among household contact children of adults having pulmonary tuberculosis in Alexandria, Egypt Aida M. Mohamed Department of Community Medicine, Faculty of Background Medicine, Alexandria University, Alexandria, Egypt Current international guidelines recommend 6–9 months of isoniazid (INH) preventive Correspondence to Aida M. Mohamed, Department of chemotherapy to prevent the development of active tuberculosis (TB) in susceptible Community Medicine, Alexandria University, children exposed to Mycobacterium tuberculosis. However, this is dependent on good Alexandria, Egypt E-mail: aida_mohey@yahoo.com adherence, as shown by previous studies. Objectives Received 3 July 2012 Accepted 4 July 2012 This study was conducted to describe the outcome of screening of contact children aged 5 years or less with household exposure to an adult pulmonary TB index case to Journal of the Egyptian Public Health Association 2012, 87:71–78 determine the prevalence and possible risk factors of infection among contact children and to determine the extent and outcome of adherence of contact children to unsupervised INH chemoprophylaxis for 6 months. Methods A descriptive facility-based cross-sectional study was conducted from March 2009 to August 2010. Research settings were three of the National TB control program chest dispensaries (primary care facilities) in Alexandria,

Journal

Journal of the Egyptian Public Health AssociationWolters Kluwer Health

Published: Aug 1, 2012

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