Clinical/Scientific Notes IgG4-RELATED SCLEROSING PACHYMENINGITIS Sang-Ho Choi, MD reprogression of the epidural mass with spinal cord CAUSING SPINAL CORD COMPRESSION Sang Hoon Lee, MD compression. Reoperation was performed using an Shin Kwang Khang, anterior retroperitoneal approach. She underwent Immunoglobulin G (IgG)4-related sclerosing dis- MD T9 –T11 right pediculectomy and partial corpec- ease is an emerging clinicopathologic entity. It is Sang Ryong Jeon, MD tomy for decompression. However, because of severe defined as a systemic disease characterized his- adhesion, the mass could not be completely re- topathologically by extensive IgG4-positive plasma moved. The pathologic specimen showed findings cell infiltration of various organs together with similar to those of the previous specimen. In the ab- T-lymphocyte infiltration. Pancreas is the most fre- sence of an exact diagnosis, empirical antituberculous quently affected organ. This disease was included medication was continued. Prednisolone 40 mg per within the category of autoimmune pancreatitis before day was also added considering the paradoxical re- the concept of IgG4-related sclerosing disease was intro- sponse of tuberculosis. One month later, during a duced. There have been several reports of patients with review of undiagnosed patients, IgG4-related scleros- IgG4-related sclerosing disease involving a wide range ing disease was suggested. Immunohistochemical
Neurology – Wolters Kluwer Health
Published: Oct 1, 2010
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