What is changed in HBV molecular epidemiology in Italy?

What is changed in HBV molecular epidemiology in Italy? INTRODUCTIONHepatitis B virus (HBV) infection is a global public health problem causing chronic hepatitis, liver cirrhosis and hepatocellular carcinoma (HCC).To date, 10 HBV genotypes have been identified, from A to J, based on a genetic diversity of at least 8% in the viral genome. These genotypes have a distinct geographic distribution worldwide (http://www.who.int/csr/disease/hepatitis/HepatitisB_whocdscsrlyo2002_2.pdf). HBV‐genotype A predominates in Northern Europe and North America, genotypes B and C in central Asia, genotype D in Mediterranean countries, genotype E in sub‐Saharan Africa and in Madagascar, genotype F in South and Central America, genotypes G and H in Mexico and some other countries in Central America and genotypes I and J in Eastern Asia. In particular, genotypes B and C prevails in highly endemic countries where perinatal HBV transmission plays an important role, whereas genotype A is frequent in areas with primarily horizontal transmission (ie, sexual contact). All genotypes are present in countries of immigration with frequencies depending on the ethnicity.A brief summary on the usefulness of serum makers during HBV infectionPresence of hepatitis B surface antigen (HBsAg) in serum indicates an ongoing HBV infection, acute, or chronic. The serum titre of anti‐HBc IgM (antibody to Hepatitis B core antigen‐HBcAg) may help to http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Medical Virology Wiley

What is changed in HBV molecular epidemiology in Italy?

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Wiley Subscription Services, Inc., A Wiley Company
Copyright
© 2018 Wiley Periodicals, Inc.
ISSN
0146-6615
eISSN
1096-9071
D.O.I.
10.1002/jmv.25027
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Abstract

INTRODUCTIONHepatitis B virus (HBV) infection is a global public health problem causing chronic hepatitis, liver cirrhosis and hepatocellular carcinoma (HCC).To date, 10 HBV genotypes have been identified, from A to J, based on a genetic diversity of at least 8% in the viral genome. These genotypes have a distinct geographic distribution worldwide (http://www.who.int/csr/disease/hepatitis/HepatitisB_whocdscsrlyo2002_2.pdf). HBV‐genotype A predominates in Northern Europe and North America, genotypes B and C in central Asia, genotype D in Mediterranean countries, genotype E in sub‐Saharan Africa and in Madagascar, genotype F in South and Central America, genotypes G and H in Mexico and some other countries in Central America and genotypes I and J in Eastern Asia. In particular, genotypes B and C prevails in highly endemic countries where perinatal HBV transmission plays an important role, whereas genotype A is frequent in areas with primarily horizontal transmission (ie, sexual contact). All genotypes are present in countries of immigration with frequencies depending on the ethnicity.A brief summary on the usefulness of serum makers during HBV infectionPresence of hepatitis B surface antigen (HBsAg) in serum indicates an ongoing HBV infection, acute, or chronic. The serum titre of anti‐HBc IgM (antibody to Hepatitis B core antigen‐HBcAg) may help to

Journal

Journal of Medical Virology – Wiley

Published: Jan 1, 2018

Keywords: ; ;

References

  • Hepatitis B virus infection in undocumented immigrants and refugees in Southern Italy: demographic, virological, and clinical features
    Coppola, N; Alessio, L; Gualdieri, L
  • Hepatitis B virus infection in immigrant populations
    Coppola, N; Alessio, L; Pisaturo, M
  • Hepatitis B virus, hepatitis C virus and human immunodeficiency virus infection in undocumented migrants and refugees in southern Italy, January 2012 to June 2013
    Coppola, N; Alessio L, Fau; Gualdieri L, Fau
  • Hepatitis B virus genotypes and variants
    Lin, CL; Kao, JH
  • The impact of viral molecular diversity on the clinical presentation and outcome of acute hepatitis B in Italy
    Sagnelli, C; Ciccozzi, M; Pisaturo, M
  • HBV endemicity in Mexico is associated with HBV genotypes H and G
    Roman, S; Panduro, A
  • Distribution of HBV genotypes F and H in Mexico and central america
    Panduro, A; Maldonado‐Gonzalez, M; Fierro, NA; Roman, S
  • Role of viral factors in the natural course and therapy of chronic hepatitis B
    Kao, JH
  • Hepatitis B virus‐related cirrhosis: natural history and treatment
    Chu, CM; Liaw, YF
  • Geographical and genetic diversity of the human hepatitis B virus
    Kurbanov, F; Tanaka, Y; Mizokami, M
  • A case‐control study for differences among hepatitis B virus infections of genotypes A (subtypes Aa and Ae) and D
    Tanaka, Y; Hasegawa, I; Kato, T
  • Hepatitis B virus infection
    Liaw, YF; Chu, CM
  • Hepatitis B virus infection in Latin America: a genomic medicine approach
    Roman, S; Jose‐Abrego, A; Fierro, NA
  • Epidemiology of acute and chronic hepatitis B and delta over the last 5 decades in Italy
    Sagnelli, E; Sagnelli, C; Pisaturo, M; Macera, M; Coppola, N
  • Surveillance for acute viral hepatitis–
    Wasley, A; Grytdal, S; Gallagher, K
  • Reducing the risk of transfusion‐transmissible viral infection through blood donor selection: the Australian experience2000 through 2006
    Polizzotto, MN; Wood, EM; Ingham, H; Keller, AJ
  • Hepatitis B virus transmission by blood transfusion during 4 years of individual‐donation nucleic acid testing in South Africa: estimated and observed window period risk
    Vermeulen, M; Dickens, C; Lelie, N
  • Differences in the availability of diagnostics and treatment modalities for chronic hepatitis B across Europe
    Ozaras, R; Corti, G; Ruta, S
  • Universal hepatitis B vaccination in Taiwan and the incidence of hepatocellular carcinoma in children. Taiwan Childhood Hepatoma Study Group
    Chang, MH; Chen, CJ; Lai, MS
  • Antiviral therapies and prospects for a cure of chronic hepatitis B
    Zoulim, F; Durantel, D
  • Incidence and routes of transmission of hepatitis B virus in England and Wales, 1995–2000: implications for immunisation policy
    Hahné, S; Ramsay, M; Balogun, K; Edmunds, WJ; Mortimer, P
  • High impact of migration on the prevalence of chronic hepatitis B in the Netherlands
    Marschall, T; Kretzschmar, M; Mangen, MJ; Schalm, S
  • Acute hepatitis B after the implementation of universal vaccination in Italy: results from 22 years of surveillance (1993–2014)
    Tosti, ME; Alfonsi, V; Lacorte, E
  • Montella M, et al.Hepatitis B and C viruses and risk of non‐Hodgkin lymphoma: a case‐control study in Italy
    Taborelli, M; Polesel, J
  • Etiology of chronic liver diseases in the Northwest of Italy, 1998 through 2014
    Saracco, GM; Evangelista, A; Fagoonee, S
  • High rate of hepatitis B viral breakthrough in elderly non‐Hodgkin lymphomas patients treated with Rituximab based chemotherapy
    Castelli, R; Ferraris, L; Pantaleo, G; Lambertenghi Deliliers, G; Cicardi, M
  • Hepatitis B virus genotypes, core promoter variants, and precore stop codon variants in patients infected chronically in North‐Eastern Italy
    Dal Molin, G; Poli, A; Crocè, LS
  • Acute hepatitis B in patients with or without underlying chronic HCV infection
    Kondilic; Furlan
  • The variety of responses within a community to infection with Australia (hepatitis B) antigen
    Blumberg, BS; Hesser, JE; Economidou, I
  • Relation of Australia and SH antigens
    Prince, AM
  • An antigen detected in the blood during the incubation period of serum hepatitis
    Prince, AM
  • Hepatitis B virus replication: novel roles for virus‐host interactions
    Nassal, M
  • Influence of universal HBV vaccination on chronic HBV infection in Italy: results of a cross‐sectional multicenter study
    Sagnelli, EA‐Ohoo; Stroffolini, T; Sagnelli, C
  • Hepatitis B virus infection among first‐time blood donors in Italy: prevalence and correlates between serological patterns and occult infection
    Romanò, L; Velati, C; Cambiè, G
  • Blood born viral infections, sexually transmitted diseases and latent tuberculosis in italian prisons: a preliminary report of a large multicenter study
    Sagnelli, E; Starnini, G; Sagnelli, C
  • Epidemiological impact of mandatory vaccination against hepatitis B in Italian young adults
    Campagna, M; Siddu, A; Meloni, A; Murru, C; Masia, G; Coppola, RC
  • A population based survey of hepatitis B virus infection in a southern Italian town
    Stroffolini, T; Guadagnino, V; Chionne, P
  • The long‐term immunogenicity of recombinant hepatitis B virus (HBV) vaccine: contribution of universal HBV vaccination in Italy
    Coppola, N; Corvino, AR; De Pascalis, S
  • Long‐term persistence of seroprotection by hepatitis B vaccination in healthcare workers of southern Italy
    Grosso, G; Mistretta, A; Marventano, S
  • Point‐of‐care screening, prevalence, and risk factors for hepatitis B infection among 3,728 mainly undocumented migrants from non‐EU countries in northern Italy
    El‐Hamad, I; Pezzoli, MC; Chiari, E
  • Prevalence of sexually transmitted diseases and hepatitis C in a survey of female sex workers in the north‐East of Italy
    Zermiani, M; Mengoli, C; Rimondo, C; Galvan, U; Cruciani, M; Serpelloni, G
  • The prevalence of sexually transmitted infections among migrant female patients in Italy
    Lagana, AS; Gavagni, V; Musubao, JV; Pizzo, A
  • Hepatitis B and immigrants: a SIMIT multicenter cross‐sectional study
    Fasano, M; Saracino, A; Carosi, G
  • Phylogenetic analysis of isolates from new cases of HBV infection in Southern Italy
    Ferraro, D; Urone, N; Pizzillo, P
  • Clinical, epidemiological and virological features of acute hepatitis B in Italy
    Zuccaro, O; Romanò, L; Mele, A
  • Molecular diversity in irregular or refugee immigrant patients with HBV‐genotype‐E infection living in the metropolitan area of Naples
    Sagnelli, C; Ciccozzi, M; Coppola, N
  • Epidemiology of HBV S‐gene mutants in the Liguria Region, Italy: implications for surveillance and detection of new escape variants
    Sticchi, L; Caligiuri, P; Cacciani, R; Alicino, C; Bruzzone, B
  • Hepatitis B virus genotypes in europe
    Schaefer, S
  • Hepatitis B virus taxonomy and hepatitis B virus genotypes
    Schaefer, S.
  • Replication of the genome of a hepatitis B‐like virus by reverse transcription of an RNA intermediate
    Summers, J; Mason, WS
  • The amino‐terminal domain of the hepadnaviral P‐gene encodes the terminal protein (genome‐linked protein) believed to prime reverse transcription
    Bartenschlager, R; Schaller, H
  • Molecular genetics of HBV infection
    Locarnini, S; Zoulim, F
  • Sodium taurocholate cotransporting polypeptide is a functional receptor for human hepatitis B and D virus
    Yan, H; Zhong, G; Xu, G
  • Hepatitis B virus with mutations in the core promoter for an e antigen‐negative phenotype in carriers with antibody to e antigen
    Okamoto, H; Tsuda, F; Akahane, Y
  • Hepatitis B virus infection: epidemiology and vaccination
    Shepard, CW; Simard, EP; Finelli, L; Fiore, AE; Bell, BP
  • Stealth and cunning: hepatitis B and hepatitis C viruses
    Wieland, SF; Chisari, FV
  • Immune effectors required for hepatitis B virus clearance
    Yang, PL; Althage, A; Chung, J
  • Characterization of hepatitis B virus (HBV)‐specific T‐cell dysfunction in chronic HBV infection
    Boni, C; Fisicaro, P; Valdatta, C
  • Restored function of HBV‐specific T cells after long‐term effective therapy with nucleos(t)ide analogues
    Boni, C; Laccabue, D; Lampertico, P
  • Cytotoxic T lymphocyte responsiveness after resolution of chronic hepatitis B virus infection
    Rehermann, B; Lau, D; Hoofnagle, JH; Chisari, FV
  • Clinical and histological events preceding hepatitis B e antigen seroconversion in chronic type B hepatitis
    Liaw, YF; Chu, CM; Su, IJ; Huang, MJ; Lin, DY; Chang‐Chien, CS
  • Acute exacerbations in Chinese patients with chronic hepatitis B virus (HBV) infection. Incidence, predisposing factors and etiology
    Lok, AS; Lai, CL
  • Impact of hepatitis B vaccination in a highly endemic area of south Italy and long‐term duration of anti‐HBs antibody in two cohorts of vaccinated individuals
    Da Villa, G; Romanò, L; Sepe, A
  • Increasing hepatitis B vaccination coverage among healthcare workers in Italy 10 years apart
    Stroffolini, T; Coppola, R; Carvelli, C
  • An assessment of the effect of hepatitis B vaccine in decreasing the amount of hepatitis B disease in Italy
    La Torre, G; Nicolotti, N; de Waure, C
  • HBV superinfection in HCV chronic carriers: a disease that is frequently severe but associated with the eradication of HCV
    Sagnelli, E; Coppola, N; Pisaturo, M
  • Acute hepatitis B 14 years after the implementation of universal vaccination in Italy: areas of improvement and emerging challenges
    Mele, A; Tosti, ME; Mariano, A
  • Hepatitis B virus‐associated membranous glomerulonephropathy
    Chen, A; Ho, YS; Tu, YC; Shieh, SD; Cheng, TC
  • Polyarteritis nodosa and extrahepatic manifestations of HBV infection: the case against autoimmune intervention in pathogenesis
    Trepo, C; Guillevin, L
  • Fulminant hepatic failure
    Berk, Pd; Popper, H
  • Worldwide epidemiology of HBV infection, disease burden, and vaccine prevention
    Lavanchy, D
  • Factors associated with fulminant liver failure during an outbreak among injection drug users with acute hepatitis B
    Garfein, RS; Bower, WA; Loney, CM
  • HBV superinfection in hepatitis C virus chronic carriers, viral interaction, and clinical course
    Sagnelli, E; Coppola, N; Messina, V
  • Anti‐HBc positivity was associated with histological cirrhosis in patients with chronic hepatitis C
    Coppola, N; Gentile, I; Pasquale, G
  • Case‐control study for the identification of virological factors associated with fulminant hepatitis B
    Kusakabe, A; Tanaka, Y; Mochida, S
  • Liver microRNA hsa‐miR‐125a‐5p in HBV chronic infection: correlation with HBV replication and disease progression
    Coppola, N; Potenza, N; Pisaturo, M
  • Distribution of hepatitis B viral genotypes and mutations in the core promoter and precore regions in acute forms of liver disease in patients from Chiba, Japan
    Imamura, T; Yokosuka, O; Kurihara, T
  • Novel subtypes (subgenotypes) of hepatitis B virus genotypes B and C among chronic liver disease patients in the Philippines
    Sakamoto, T; Tanaka, Y; Orito, E
  • Association of hepatitis B virus subgenotypes and basal core promoter/precore region variants with the clinical features of patients with acute hepatitis
    Hayashi, K; Katano, Y; Takeda, Y
  • Variations of hepatitis B virus precore/core gene sequence in acute and fulminant hepatitis B
    Aye, TT; Uchida, T; Becker, SO
  • [Fulminant hepatitis B and mutant virus]
    Omata, M; Ebata, T
  • Probable implication of mutations of the X open reading frame in the onset of fulminant hepatitis B
    Kaneko, M; Uchida, T; Moriyama, M
  • Hepatitis B virus strains with mutations in the core promoter in patients with fulminant hepatitis
    Sato, S; Suzuki, K; Akahane, Y
  • Clinical outcome and virological characteristics of hepatitis B‐related acute liver failure in the United States
    Wai, CT; Fontana, RJ; Polson, J
  • Lamivudine‐resistant HBV strain rtM204V/I in acute hepatitis B
    Coppola, N; Tonziello, G; Colombatto, P
  • Factors affecting the changes in molecular epidemiology of acute hepatitis B in a Southern Italian area
    Coppola, N; Masiello, A; Tonziello, G
  • Clinical and virological characteristics associated with severe acute hepatitis B
    Coppola, N; Sagnelli, C; Pisaturo, M
  • Long‐term outcome of chronic hepatitis B in Caucasian patients: mortality after 25 years
    Fattovich, G; Olivari, N; Pasino, M; D'Onofrio, M; Martone, E; Donato, F
  • Natural history of chronic hepatitis B in Euro‐Mediterranean and African countries
    Hadziyannis, SJ
  • Virologic and clinical expressions of reciprocal inhibitory effect of hepatitis B, C, and delta viruses in patients with chronic hepatitis
    Sagnelli, E; Coppola, N; Scolastico, C
  • New insight in the pathobiology of hepatitis B virus infection
    Dandri, M; Locarnini, S
  • Preserved T‐cell function in children and young adults with immune‐tolerant chronic hepatitis B
    Kennedy, PTF; Sandalova, E; Jo, J
  • Serum hepatitis B virus DNA levels and liver histology in inactive HBsAg carriers
    Martinot‐Peignoux, M; Boyer, N; Colombat, M
  • The role of quantitative hepatitis B surface antigen revisited
    Cornberg, M; Wong, VW; Locarnini, S; Brunetto, M; Janssen, HL; Chan, HL
  • Reactivation of overt and occult hepatitis B infection in various immunosuppressive settings
    Coppola, N; Tonziello, G; Pisaturo, M
  • Statements from the Taormina expert meeting on occult hepatitis B virus infection
    Raimondo, G; Allain, JP; Brunetto, MR
  • Hepatitis B virus maintains its pro‐oncogenic properties in the case of occult HBV infection
    Pollicino, T; Squadrito, G; Cerenzia, G
  • Hepatitis C virus genotype 1b as a major risk factor associated with hepatocellular carcinoma in patients with cirrhosis: a seventeen‐year prospective cohort study
    Bruno, S; Crosignani, A; Maisonneuve, P; Rossi, S; Silini, E; Mondelli, MU
  • A recent epidemiological cluster of acute hepatitis B genotype F1b infection in a restricted geographical area of Italy
    Pollicita, M; Alteri, C; Bellocchi, MC
  • Enigmatic origin of hepatitis B virus: an ancient travelling companion or a recent encounter
    Zehender, G; Ebranati, E; Gabanelli, E
  • Different evolutionary rates and epidemic growth of hepatitis B virus genotypes A and D
    Zehender, G; De Maddalena, C; Giambelli, C
  • Molecular epidemiology and phylogenetic analysis of Hepatitis B virus in a group of migrants in Italy
    Villano, U; Lo Presti, A; Equestre, M
  • Evolutionary dynamics of HBV‐D1 genotype epidemic in Turkey
    Ciccozzi, M; Ciccaglione, AR; Lo Presti, A
  • Reconstruction of the epidemic history of hepatitis B virus genotype D in Albania
    Zehender, G; Shkjezi, R; Ebranati, E
  • Spatial and temporal dynamics of hepatitis B virus D genotype in Europe and the Mediterranean Basin
    Zehender, G; Ebranati, E; Gabanelli, E

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