Utility values for childhood obesity interventions: a systematic review and meta‐analysis of the evidence for use in economic evaluation

Utility values for childhood obesity interventions: a systematic review and meta‐analysis of... Rigorous estimates of preference‐based utilities are important inputs into economic evaluations of childhood obesity interventions, yet no published review currently exists examining utility by weight status in paediatric populations. A comprehensive systematic literature review and meta‐analysis was therefore undertaken, pooling data on preference‐based health state utilities by weight status in children using a random‐effects model. Tests for heterogeneity were performed, and publication bias was assessed. Of 3,434 potentially relevant studies identified, 11 met our eligibility criteria. Estimates of Cohen's d statistic suggested a small effect of weight status on preference‐based utilities. Mean utility values were estimated as 0.85 (95% uncertainty interval [UI] 0.84–0.87), 0.83 (95% UI 0.81–0.85), 0.82 (95% UI 0.79–0.84) and 0.83 (95% UI 0.80–0.86) for healthy weight, overweight, obese and overweight/obese states, respectively. Meta‐analysis of studies reporting utility values for both healthy weight and overweight/obese participants found a statistically significant weighted mean difference (0.015, 95% UI 0.003–0.026). A small but statistically significant difference was also estimated between healthy weight and overweight participants (0.011, 95% UI 0.004–0.018). Study findings suggest that paediatric‐specific benefits of obesity interventions may not be well reflected by available utility measures, potentially underestimating cost‐effectiveness if weight loss in childhood/adolescence improves health or well‐being. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Obesity Reviews Wiley

Utility values for childhood obesity interventions: a systematic review and meta‐analysis of the evidence for use in economic evaluation

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Publisher
Wiley
Copyright
© 2018 World Obesity Federation
ISSN
1467-7881
eISSN
1467-789X
DOI
10.1111/obr.12672
Publisher site
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Abstract

Rigorous estimates of preference‐based utilities are important inputs into economic evaluations of childhood obesity interventions, yet no published review currently exists examining utility by weight status in paediatric populations. A comprehensive systematic literature review and meta‐analysis was therefore undertaken, pooling data on preference‐based health state utilities by weight status in children using a random‐effects model. Tests for heterogeneity were performed, and publication bias was assessed. Of 3,434 potentially relevant studies identified, 11 met our eligibility criteria. Estimates of Cohen's d statistic suggested a small effect of weight status on preference‐based utilities. Mean utility values were estimated as 0.85 (95% uncertainty interval [UI] 0.84–0.87), 0.83 (95% UI 0.81–0.85), 0.82 (95% UI 0.79–0.84) and 0.83 (95% UI 0.80–0.86) for healthy weight, overweight, obese and overweight/obese states, respectively. Meta‐analysis of studies reporting utility values for both healthy weight and overweight/obese participants found a statistically significant weighted mean difference (0.015, 95% UI 0.003–0.026). A small but statistically significant difference was also estimated between healthy weight and overweight participants (0.011, 95% UI 0.004–0.018). Study findings suggest that paediatric‐specific benefits of obesity interventions may not be well reflected by available utility measures, potentially underestimating cost‐effectiveness if weight loss in childhood/adolescence improves health or well‐being.

Journal

Obesity Reviews – Wiley

Published: Jan 1, 2018

Keywords: ; ; ;

References

  • Report of the Commission on Ending Childhood Obesity
  • Guidelines for Preparing Submissions to the Pharmaceutical Benefits Advisory Committee (PBAC)
  • Developing NICE Guidelines: The Manual United Kingdom 2017
  • Cost–utility analysis
    Robinson, R
  • Health outcomes in economic evaluation: the QALY and utilities
    Whitehead, SJ; Ali, S
  • Methods for the Economic Evaluation of Health Care Programmes
    Drummond, MF; Sculpher, MJ; Torrance, GW; O'Brien, BJ; Stoddart, GL
  • QALYs: the basics
    Weinstein, MC; Torrance, G; McGuire, A
  • Preferences for health outcomes and cost–utility analysis
    Torrance, GW
  • Review of utility values for economic modeling in type 2 diabetes
    Beaudet, A; Clegg, J; Thuresson, P‐O; Lloyd, A; McEwan, P
  • The estimation of utility weights in cost–utility analysis for mental disorders: a systematic review
    Sonntag, M; König, H‐H; Konnopka, A
  • Utility values associated with advanced or metastatic non‐small cell lung cancer: data needs for economic modeling
    Brown, J; Cook, K; Adamski, K
  • One thousand health‐related quality‐of‐life estimates
    Tengs, TO; Wallace, A
  • The impact of body weight on patient utilities with or without type 2 diabetes: a review of the medical literature
    Dennett, SL; Boye, KS; Yurgin, NR
  • Cost effectiveness of IDegLira vs. alternative basal insulin intensification therapies in patients with type 2 diabetes mellitus uncontrolled on basal insulin in a UK setting
    Davies, MJ; Glah, D; Chubb, B; Konidaris, G; McEwan, P
  • A systematic review and critical assessment of health state utilities: weight change and type 2 diabetes mellitus
    Doyle, S; Lloyd, A; Moore, L; Ray, J; Gray, A
  • Measuring health utilities in children and adolescents: a systematic review of the literature
    Thorrington, D; Eames, K
  • Review of the development and application of generic multi‐attribute utility instruments for paediatric populations
    Chen, G; Ratcliffe, JA
  • Methodological issues raised by preference‐based approaches to measuring the health status of children
    Petrou, S
  • Estimating preference‐based Health Utilities Index Mark 3 utility scores for childhood conditions in England and Scotland
    Petrou, S; Kupek, E
  • Sources and characteristics of utility weights for economic evaluation of pediatric vaccines: a systematic review
    Herdman, M; Cole, A; Hoyle, CK; Coles, V; Carroll, S; Devlin, N
  • Systematic review and meta‐analysis of childhood health utilities
    Kwon, J; Kim, SW; Ungar, WJ; Tsiplova, K; Madan, J; Petrou, SA
  • Effect of multidisciplinary interventions on quality of life in obese children: a systematic review and meta‐analysis
    Kelly, A; Ligthart, M; Paulis, WD; Djasmo, D; Koes, BW; Middelkoop, M
  • Meta‐analysis of the association between body mass index and health‐related quality of life among children and adolescents, assessed using the pediatric quality of life inventory index
    Ul‐Haq, Z; Mackay, DF; Fenwick, E; Pell, JP
  • Systematic searching and selection of health state utility values from the literature
    Papaioannou, D; Brazier, J; Paisley, S
  • Preferred reporting items for systematic reviews and meta‐analyses: the PRISMA statement
    Moher, D; Liberati, A; Tetzlaff, J; Altman, DG
  • Paediatric Economic Database Evaluation (PEDE)
  • A meta‐analysis of health state valuations for people with diabetes: explaining the variation across methods and implications for economic evaluation
    Lung, TW; Hayes, AJ; Hayen, A; Farmer, A; Clarke, PM
  • Cochrane Handbook for Systematic Reviews of Interventions
  • A systematic review and critical assessment of health state utilities
    Doyle, S; Lloyd, A; Moore, L; Ray, J; Gray, A
  • MetaXL User Guide
    Barendregt, JJ; Doi, SA
  • The effect size index: d. Statistical power analysis for the behavioral
    Cohen, J
  • Prevention of eating disorders: a systematic review and meta‐analysis
    Le, LK‐D; Barendregt, JJ; Hay, P; Mihalopoulos, C
  • Physical activity, quality of life, weight status and diet in adolescents
    Boyle, SE; Jones, GL; Walters, SJ
  • Is utility‐based quality of life in children aged 6–7 years affected by body mass index (BMI)?
    Canaway, AG; Frew, EJ
  • BMI, health behaviors, and quality of life in children and adolescents: a school‐based study
    Chen, G; Ratcliffe, J; Olds, T; Magarey, A; Jones, M; Leslie, E
  • Is utility‐based quality of life associated with overweight in children? Evidence from the UK WAVES randomised controlled study
    Frew, EJ; Pallan, M; Lancashire, E; Hemming, K; Adab, P
  • Consolidated Health Economic Evaluation Reporting Standards (CHEERS) statement
    Husereau, D; Drummond, M; Petrou, S
  • Health state preferences associated with weight status in children and adolescents
    Belfort, MB; Zupancic, JAF; Riera, KM; Turner, JHG; Prosser, LA
  • The effect of gender and age on the association between weight status and health‐related quality of life in Australian adolescents
    Bolton, K; Kremer, P; Rossthorn, N
  • Utility‐based quality of life of overweight and obese adolescents
    Keating, CL; Moodie, ML; Richardson, J; Swinburn, BA
  • Cardiometabolic risk factors and quality of life in severely obese children and adolescents in the Netherlands
    Makkes, S; Renders, CM; Bosmans, JE; Baan‐Slootweg, OH; Seidell, JC
  • Obesity and preference‐weighted quality of life of ethnically diverse middle school children: the HEALTHY study
    Treviño, RP; Pham, TH; Edelstein, SL
  • Economic evaluation of a community‐based obesity prevention program in children: the APPLE project
    McAuley, KA; Taylor, RW; Farmer, VL
  • Randomised controlled trial and economic evaluation of the ‘Families for Health’ programme to reduce obesity in children
    Robertson, W; Fleming, J; Kamal, A
  • Construction of the descriptive system for the Assessment of Quality of Life AQoL‐6D utility instrument
    Richardson, JR; Peacock, SJ; Hawthorne, G; Iezzi, A; Elsworth, G; Day, NA
  • Predicting time trade‐off health state valuations of adolescents in four Pacific countries using the Assessment of Quality‐of‐Life (AQoL‐6D) instrument
    Moodie, M; Richardson, J; Rankin, B; Iezzi, A; Sinha, K
  • Measuring and Valuing Health, The Development of a Paediatric Health Related Quality of Life Measure for Use in Economic Evaluation: The Child Health Utility 9D (CHU 9D)
  • Valuation of the Child Health Utility 9D index
    Stevens, K
  • Developing adolescent‐specific health state values for economic evaluation
    Ratcliffe, J; Flynn, T; Terlich, F; Stevens, K; Brazier, J; Sawyer, M
  • EQ‐5D: About The Netherlands
  • A Social Tariff for EuroQol: Results from a UK General Population Survey
    Dolan, P; Gudex, C; Kind, P; Williams, A
  • EQ‐5D‐3L: About The Netherlands
  • Measuring the quality of life in economic evaluations: the Dutch EQ‐5D tariff
    Lamers, L; Stalmeier, P; McDonnell, J; Krabbe, P; Busschbach, J
  • Multiattribute utility function for a comprehensive health status classification system: Health Utilities Index Mark 2
    Torrance, GW; Feeny, DH; Furlong, WJ; Barr, RD; Zhang, Y; Wang, Q
  • Multiattribute and single‐attribute utility functions for the Health Utilities Index Mark 3 system
    Feeny, D; Furlong, W; Torrance, GW
  • Establishing a standard definition for child overweight and obesity worldwide: international survey
    Cole, TJ; Bellizzi, MC; Flegal, KM; Dietz, WH
  • Age‐specific impact of obesity on prevalence and costs of diabetes and dyslipidemia
    Finkelstein, EA; Brown, DS; Trogdon, JG; Segel, JE; Ben‐Joseph, RH
  • Comparative Quantification of Health Risks: Global and Regional Burden of Disease Attributable to Selected Major Risk Factors
    Ezzati, M; Lopez, AD; Rodgers, A; Murray, CJ
  • systematic review of reviews: exploring the relationship between obesity, weight loss and health‐related quality of life. Clin
    Kolotkin, R; Andersen, JA
  • The relationship between body mass index and health‐related quality of life: comparing the EQ‐5D, EuroQol VAS and SF‐6D
    Sach, TH; Barton, GR; Doherty, M; Muir, KR; Jenkinson, C; Avery, AJ
  • The effect of weight status, lifestyle, and body image perception on health‐related quality of life in children: a quantile approach
    Petracci, E; Cavrini, G
  • Is central obesity associated with poorer health and health‐related quality of life in primary school children? Cross‐sectional results from the Baden‐Württemberg Study
    Kesztyües, D; Wirt, T; Kobel, S
  • Illness and determinants of health‐related quality of life in a cross‐sectional sample of schoolchildren in different weight categories
    Kesztyüs, D; Schreiber, A; Kobel, S
  • Diet quality, physical activity, body weight and health‐related quality of life among grade 5 students in Canada
    Wu, X; Ohinmaa, A; Veugelers, PJ
  • Reducing unhealthy weight gain in Fijian adolescents: results of the Healthy Youth Healthy Communities study
    Kremer, P; Waqa, G; Vanualailai, N
  • Self‐esteem and quality of life in obese children and adolescents: a systematic review
    Griffiths, LJ; Parsons, TJ; Hill, AJ
  • Quality of life in overweight and obese children and adolescents: a literature review
    Buttitta, M; Iliescu, C; Rousseau, A; Guerrien, A
  • Health‐related quality of life in obese children and adolescents
    Tsiros, MD; Olds, T; Buckley, JD
  • Quality of life improves in children and adolescents during a community‐based overweight and obesity treatment
    Mollerup, PM; Nielsen, TR; Bøjsøe, C; Kloppenborg, JT; Baker, JL; Holm, J‐C
  • Change in health‐related quality of life in the context of pediatric obesity interventions: a meta‐analytic review
    Steele, RG; Gayes, LA; Dalton, WT; Smith, C; Maphis, L; Conway‐Williams, E
  • Comparing and explaining differences in the magnitude, content, and sensitivity of utilities predicted by the EQ‐5D, SF‐6D, HUI 3, 15D, QWB, and AQoL‐8D multiattribute utility instruments
    Richardson, J; Khan, MA; Iezzi, A; Maxwell, A
  • Quality‐adjusted life‐years lack quality in pediatric care: a critical review of published cost–utility studies in child health
    Griebsch, I; Coast, J; Brown, J
  • The PedsQL Measurement Model for the Pediatric Quality of Life Inventory 2017
    Varni, JW
  • Mapping CHU9D Utility Scores from the PedsQLTM 4.0 SF‐15
    Mpundu‐Kaambwa, C; Chen, G; Russo, R; Stevens, K; Petersen, KD; Ratcliffe, J
  • Mapping EQ‐5D utility scores from the PedsQL™ generic core scales
    Khan, KA; Petrou, S; Rivero‐Arias, O; Walters, SJ; Boyle, SE
  • Cost effectiveness of childhood obesity interventions: evidence and methods for CHOICES
    Gortmaker, SL; Long, MW; Resch, SC
  • Cost‐effectiveness of a nutrition education curriculum intervention in elementary schools
    Graziose, MM; Koch, PA; Wang, YC; Lee Gray, H; Contento, IR
  • Modelled health benefits of a sugar‐sweetened beverage tax across different socioeconomic groups in Australia: a cost‐effectiveness and equity analysis
    Lal, A; Mantilla‐Herrera, AM; Veerman, L
  • Critical appraisal of health‐state utility values used in breast cancer‐related cost–utility analyses
    Nerich, V; Saing, S; Gamper, E‐M
  • meta‐analysis for utility values appropriate given the potential impact different elicitation methods have on values?
    Peasgood, T; Brazier, JI
  • Defining Childhood Obesity
  • Growth Reference 5–19 Years
  • Body mass index reference curves for the UK, 1990
    Cole, TJ; Freeman, JV; Preece, MA
  • Continuing positive secular growth change in The Netherlands 1955–1997
    Fredriks, AM; Van Buuren, S; Burgmeijer, RJ

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