Access the full text.
Sign up today, get DeepDyve free for 14 days.
D. Wong, F. Bymaster, J. Horng, B. Molloy (1975)
A new selective inhibitor for uptake of serotonin into synaptosomes of rat brain: 3-(p-trifluoromethylphenoxy). N-methyl-3-phenylpropylamine.The Journal of pharmacology and experimental therapeutics, 193 3
Collard Collard, Evans Evans, Suter Suter, Wilkinson Wilkinson (1982)
The stimulus induced release of 5‐hydroxytryptamine and trytophan from superfused rat brian synaptosomesJ. Neural Transm., 53
U. Schacht, M. Leven (1984)
Stereoselective inhibition of synaptosomal catecholamine uptake by nomifensine.European journal of pharmacology, 98 2
(1966)
Lactic dehydrogenase, in Methods in Enzymology
M. Raiteri, G. Bonanno, M. Marchi, G. Maura (1984)
Is there a functional linkage between neurotransmitter uptake mechanisms and presynaptic receptors?The Journal of pharmacology and experimental therapeutics, 231 3
M. Bradford (1976)
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.Analytical biochemistry, 72
U. Moeser (1964)
LACTIC DEHYDROGENASE.The Journal of the Maine Medical Association, 55
M. Waller, J. Richter (1980)
Effects of pentobarbital and Ca2+ on the resting and K+-stimulated release of several endogenous neurotransmitters from rat midbrain slices.Biochemical pharmacology, 29 16
(1984)
Characteristics of t r y g tophan accumulation by isolated rat forebrain synapto - somes
C. Cotman, D. Matthews (1971)
Synaptic plasma membranes from rat brain synaptosomes: isolation and partial characterization.Biochimica et biophysica acta, 249 2
Forn Forn (1972)
Active transport of 5‐hydroxyindoleacetic acid by the rabbit choroid plexus in vitro, BiochemPharmacol., 21
Salvaterro Salvaterro, Matthews Matthews (1980)
Isolation of rat brain subcellular fraction enriched in putative neurotransmitter receptors and synaptic junctionsNeurochem. Res., 5
M. Verity (1972)
CATION MODULATION OF SYNAPTOSOMAL RESPIRATIONJournal of Neurochemistry, 19
J. Forn (1972)
Active transport of 5-hydroxyindoleacetic acid by the rabbit choroid plexus in vitro. Blockade by probenecid and metabolic inhibitors.Biochemical pharmacology, 21 5
E. Gray, V. Whittaker (1962)
The isolation of nerve endings from brain: an electron-microscopic study of cell fragments derived by homogenization and centrifugation.Journal of anatomy, 96
Richard Knowles, C. Pogson (1984)
Characteristics of Tryptophan Accumulation by Isolated Rat Forebrain SynaptosomesJournal of Neurochemistry, 42
(1980)
The characteristics of serotonin uptake systems , in Biology of Serotonergic Transmission (
S. Urwyler, J. Wartburg (1981)
Uptake and metabolism of catecholamines in rat brain synaptosomes: studies on the contribution of monoamine oxidase.Biochemical pharmacology, 30 20
Sidney 'and, P. Lipton (1982)
Vasopressin augments depolarization-induced release and synthesis of serotonin in hippocampal slices, 2
(1982)
The characteristics of serotonin uptake systems
W. Wolf, D. Kuhn (1983)
Simultaneous determination of 5-hydroxytryptamine, its amino acid precursors and acid metabolite in discrete brain regions by high-performance liquid chromatography with fluorescence detection.Journal of chromatography, 275 1
Abstract: An HPLC assay with fluorometric detection has been developed that is sensitive enough to measure simultaneously endogenous levels of tryptophan, serotonin (5‐hydroxytryptamine, or 5‐HT), and 5‐hydroxyindoleacetic acid (5‐HIAA) inside synaptosomes as well as that released into the incubation medium. Using this assay, we have observed that tryptophan is rapidly taken up by synaptosomes and turned over to 5‐HIAA without a concurrent release of 5‐HT. Exogenous 5‐HT is also rapidly taken up, and, within 20–30 min, 80% of the 5‐HT is deaminated. Veratridine induces release of both tryptophan and 5‐HT from synaptosomes. Changes in the disposition of exogenous tryptophan or 5‐HT can be completely accounted for by uptake or by stoichiometric changes in metabolites. This assay method should be valuable in the study of 5‐HT pools and in the determination of from which pool 5‐HT release occurs.
Journal of Neurochemistry – Wiley
Published: Jan 1, 1986
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.