Transoral robotic surgery for oropharyngeal carcinoma: Surgical margins and oncologic outcomes

Transoral robotic surgery for oropharyngeal carcinoma: Surgical margins and oncologic outcomes INTRODUCTIONTreatment for oropharyngeal squamous cell carcinoma (SCC) consists of complete surgical resection, radiotherapy (RT), RT and chemotherapy (CRT), or combinations thereof. In the past decade, providers have recognized that human papillomavirus (HPV)‐mediated oropharyngeal SCC often responds exceedingly well to treatment regardless of modality; yet, the treatment choice itself may result in long‐term morbidity. This has generated interest in “deintensification” strategies that seek to maintain oncologic outcomes while minimizing treatment‐related morbidity.Since 2007, our institution has used transoral robotic surgery (TORS) ± adjuvant RT or CRT based on pathologic staging for patients with surgically resectable oropharyngeal SCC. The TORS‐based therapy is used with the goal of complete surgical resection with clear microscopic margins. We have presented preliminary studies with this technique, but this article represents long‐term experience using TORS‐based therapy with frozen section margin clearance for oropharyngeal SCC in what we believe to be the largest single institutional review presented to date. Herein, we specifically investigate the oncologic outcomes experienced by patients treated with: (1) TORS alone; (2) TORS + RT (surgery [S]‐RT); and (3) TORS + CRT (S‐CRT) and analyze factors that may influence these outcomes.MATERIALS AND METHODSPatient selectionAfter institutional review board approval (14‐004693) all patients who underwent TORS for http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Head & Neck: Journal for the Sciences & Specialties of the Head and Neck Wiley

Loading next page...
 
/lp/wiley/transoral-robotic-surgery-for-oropharyngeal-carcinoma-surgical-margins-Er0A01YI0l
Publisher
Wiley Subscription Services, Inc., A Wiley Company
Copyright
© 2018 Wiley Periodicals, Inc.
ISSN
1043-3074
eISSN
1097-0347
D.O.I.
10.1002/hed.25055
Publisher site
See Article on Publisher Site

Abstract

INTRODUCTIONTreatment for oropharyngeal squamous cell carcinoma (SCC) consists of complete surgical resection, radiotherapy (RT), RT and chemotherapy (CRT), or combinations thereof. In the past decade, providers have recognized that human papillomavirus (HPV)‐mediated oropharyngeal SCC often responds exceedingly well to treatment regardless of modality; yet, the treatment choice itself may result in long‐term morbidity. This has generated interest in “deintensification” strategies that seek to maintain oncologic outcomes while minimizing treatment‐related morbidity.Since 2007, our institution has used transoral robotic surgery (TORS) ± adjuvant RT or CRT based on pathologic staging for patients with surgically resectable oropharyngeal SCC. The TORS‐based therapy is used with the goal of complete surgical resection with clear microscopic margins. We have presented preliminary studies with this technique, but this article represents long‐term experience using TORS‐based therapy with frozen section margin clearance for oropharyngeal SCC in what we believe to be the largest single institutional review presented to date. Herein, we specifically investigate the oncologic outcomes experienced by patients treated with: (1) TORS alone; (2) TORS + RT (surgery [S]‐RT); and (3) TORS + CRT (S‐CRT) and analyze factors that may influence these outcomes.MATERIALS AND METHODSPatient selectionAfter institutional review board approval (14‐004693) all patients who underwent TORS for

Journal

Head & Neck: Journal for the Sciences & Specialties of the Head and NeckWiley

Published: Jan 1, 2018

Keywords: ; ; ; ;

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

Monthly Plan

  • Read unlimited articles
  • Personalized recommendations
  • No expiration
  • Print 20 pages per month
  • 20% off on PDF purchases
  • Organize your research
  • Get updates on your journals and topic searches

$49/month

Start Free Trial

14-day Free Trial

Best Deal — 39% off

Annual Plan

  • All the features of the Professional Plan, but for 39% off!
  • Billed annually
  • No expiration
  • For the normal price of 10 articles elsewhere, you get one full year of unlimited access to articles.

$588

$360/year

billed annually
Start Free Trial

14-day Free Trial