The Viability of Human Blood Stored in Phosphate Adenine Media

The Viability of Human Blood Stored in Phosphate Adenine Media The addition of .03 M phosphate ion and adenine to stored blood produces a profound effect on erythrocyte ATP. At the end of 50–65 days storage, the ATP content of such blood is approximately 40% higher than that of blood supplemented with adenine alone. Despite the large increment of ATP, there was little, if any, difference in the viability of blood stored in these solutions. Thus, after 50 days storage, the ATP content is no longer the limiting factor in maintaining erythrocyte viability. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Transfusion Wiley

The Viability of Human Blood Stored in Phosphate Adenine Media

Transfusion, Volume 7 (6) – Nov 12, 1967

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Publisher
Wiley
Copyright
1967 AABB
ISSN
0041-1132
eISSN
1537-2995
D.O.I.
10.1111/j.1537-2995.1967.tb04875.x
Publisher site
See Article on Publisher Site

Abstract

The addition of .03 M phosphate ion and adenine to stored blood produces a profound effect on erythrocyte ATP. At the end of 50–65 days storage, the ATP content of such blood is approximately 40% higher than that of blood supplemented with adenine alone. Despite the large increment of ATP, there was little, if any, difference in the viability of blood stored in these solutions. Thus, after 50 days storage, the ATP content is no longer the limiting factor in maintaining erythrocyte viability.

Journal

TransfusionWiley

Published: Nov 12, 1967

References

  • Some in vitro effects of adenine added to stored blood
    Bishop, Bishop
  • A citrate‐phosphate‐dextrose solution for the preservation of human blood
    Gibson, Gibson; Rees, Rees; McManus, McManus; Scheitlin, Scheitlin
  • Comparison of blood stored in ACD and in a solution containing heparin, phosphate, glucose and adenine
    Kozek, Kozek; Bishop, Bishop
  • Observations on the effects of purine nucleosides on red cell preservation
    Mollison, Mollison; Robinson, Robinson
  • Adenine in red cell preservation
    Simon, Simon; Chapman, Chapman; Finch, Finch

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