INTRODUCTIONThe frequency of early detection of focal ground‐glass opacity nodules (GGN) has been increasing due to computed tomography (CT) screening programs and with advances in the quality of high resolution computed tomography (HRCT). Persistent GGN are indicative of focal fibrosis, atypical adenomatous hyperplasia (AAH), or early stage lung cancer. While most lung cancer with a GGN is diagnosed as adenocarcinoma in situ (AIS) or minimally invasive adenocarcinoma (MIA), in some cases, it can also be diagnosed as invasive adenocarcinoma. To date, other than measuring the size of the solid component on HRCT, no factors have been identified for preoperatively predicting which category—AIS, MIA, or invasive adenocarcinoma—lung cancer with a GGN would fall into after a postoperative pathological examination.Since preoperative positron emission tomography/CT (PET/CT) generates relatively clear information on lymph node metastasis or metastasis to other organs before tissue confirmation, it is recommended in all patients with lung cancer who are scheduled to undergo surgery. However, the efficacy of PET/CT in lung cancer with a GGN is controversial because this cancer is less likely to present hypermetabolism at the main lesions or lymph node than exclusively solid tumors.However, if the maximum standardized uptake values (SUVmax) of main lesions are different
Journal of Surgical Oncology – Wiley
Published: Jan 1, 2018
Keywords: ; ; ;
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