The maximum standardized uptake value of preoperative positron emission tomography/computed tomography in lung adenocarcinoma with a ground‐glass opacity component of less than 30 mm

The maximum standardized uptake value of preoperative positron emission tomography/computed... INTRODUCTIONThe frequency of early detection of focal ground‐glass opacity nodules (GGN) has been increasing due to computed tomography (CT) screening programs and with advances in the quality of high resolution computed tomography (HRCT). Persistent GGN are indicative of focal fibrosis, atypical adenomatous hyperplasia (AAH), or early stage lung cancer. While most lung cancer with a GGN is diagnosed as adenocarcinoma in situ (AIS) or minimally invasive adenocarcinoma (MIA), in some cases, it can also be diagnosed as invasive adenocarcinoma. To date, other than measuring the size of the solid component on HRCT, no factors have been identified for preoperatively predicting which category—AIS, MIA, or invasive adenocarcinoma—lung cancer with a GGN would fall into after a postoperative pathological examination.Since preoperative positron emission tomography/CT (PET/CT) generates relatively clear information on lymph node metastasis or metastasis to other organs before tissue confirmation, it is recommended in all patients with lung cancer who are scheduled to undergo surgery. However, the efficacy of PET/CT in lung cancer with a GGN is controversial because this cancer is less likely to present hypermetabolism at the main lesions or lymph node than exclusively solid tumors.However, if the maximum standardized uptake values (SUVmax) of main lesions are different http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Surgical Oncology Wiley

The maximum standardized uptake value of preoperative positron emission tomography/computed tomography in lung adenocarcinoma with a ground‐glass opacity component of less than 30 mm

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Publisher
Wiley Subscription Services, Inc., A Wiley Company
Copyright
© 2018 Wiley Periodicals, Inc.
ISSN
0022-4790
eISSN
1096-9098
D.O.I.
10.1002/jso.24857
Publisher site
See Article on Publisher Site

Abstract

INTRODUCTIONThe frequency of early detection of focal ground‐glass opacity nodules (GGN) has been increasing due to computed tomography (CT) screening programs and with advances in the quality of high resolution computed tomography (HRCT). Persistent GGN are indicative of focal fibrosis, atypical adenomatous hyperplasia (AAH), or early stage lung cancer. While most lung cancer with a GGN is diagnosed as adenocarcinoma in situ (AIS) or minimally invasive adenocarcinoma (MIA), in some cases, it can also be diagnosed as invasive adenocarcinoma. To date, other than measuring the size of the solid component on HRCT, no factors have been identified for preoperatively predicting which category—AIS, MIA, or invasive adenocarcinoma—lung cancer with a GGN would fall into after a postoperative pathological examination.Since preoperative positron emission tomography/CT (PET/CT) generates relatively clear information on lymph node metastasis or metastasis to other organs before tissue confirmation, it is recommended in all patients with lung cancer who are scheduled to undergo surgery. However, the efficacy of PET/CT in lung cancer with a GGN is controversial because this cancer is less likely to present hypermetabolism at the main lesions or lymph node than exclusively solid tumors.However, if the maximum standardized uptake values (SUVmax) of main lesions are different

Journal

Journal of Surgical OncologyWiley

Published: Jan 1, 2018

Keywords: ; ; ;

References

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