The impact of visceral adipose tissue amount on the adequacy of lymph node retrieval in colorectal cancer surgery

The impact of visceral adipose tissue amount on the adequacy of lymph node retrieval in... INTRODUCTIONAs the obese population increases, patients who receive surgery for colorectal cancer (CRC) are more likely to be obese. Clinically, for CRC patients who undergo curative colectomy, the patient's lymph node (LN) metastasis status is a crucial prognostic factor. Therefore, the American Joint Committee on Cancer (AJCC) recommends that for precise pathological staging, at least 12 LNs should be retrieved from the resected specimen for microscopic evaluation. However, the total number of retrieved LNs could be influenced by patient factors (such as age, sex, and intra‐abdominal anatomy), as well as the affected cancer characteristics, the operative procedure, and the LN isolation process from the resected specimen. In addition to these factors, obesity might have a significant influence on the outcome. Few reports have examined this subject, and most investigations have used body mass index (BMI), which is calculated by height and body weight, to define obesity. Few studies have defined obesity according to the quantity of visceral adipose tissue (VAT). In this study, we analyzed the effect of obesity, defined by BMI, VAT, and subcutaneous adipose tissue (SAT), on the number of retrieved LNs and the adequacy of LN retrieval (adequate, ≥12 LNs; inadequate, <12 LNs). We compared the http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Surgical Oncology Wiley

The impact of visceral adipose tissue amount on the adequacy of lymph node retrieval in colorectal cancer surgery

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Publisher
Wiley Subscription Services, Inc., A Wiley Company
Copyright
© 2018 Wiley Periodicals, Inc.
ISSN
0022-4790
eISSN
1096-9098
D.O.I.
10.1002/jso.24876
Publisher site
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Abstract

INTRODUCTIONAs the obese population increases, patients who receive surgery for colorectal cancer (CRC) are more likely to be obese. Clinically, for CRC patients who undergo curative colectomy, the patient's lymph node (LN) metastasis status is a crucial prognostic factor. Therefore, the American Joint Committee on Cancer (AJCC) recommends that for precise pathological staging, at least 12 LNs should be retrieved from the resected specimen for microscopic evaluation. However, the total number of retrieved LNs could be influenced by patient factors (such as age, sex, and intra‐abdominal anatomy), as well as the affected cancer characteristics, the operative procedure, and the LN isolation process from the resected specimen. In addition to these factors, obesity might have a significant influence on the outcome. Few reports have examined this subject, and most investigations have used body mass index (BMI), which is calculated by height and body weight, to define obesity. Few studies have defined obesity according to the quantity of visceral adipose tissue (VAT). In this study, we analyzed the effect of obesity, defined by BMI, VAT, and subcutaneous adipose tissue (SAT), on the number of retrieved LNs and the adequacy of LN retrieval (adequate, ≥12 LNs; inadequate, <12 LNs). We compared the

Journal

Journal of Surgical OncologyWiley

Published: Jan 1, 2018

Keywords: ; ; ;

References

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