The impact of visceral adipose tissue amount on the adequacy of lymph node retrieval in colorectal cancer surgery

The impact of visceral adipose tissue amount on the adequacy of lymph node retrieval in... INTRODUCTIONAs the obese population increases, patients who receive surgery for colorectal cancer (CRC) are more likely to be obese. Clinically, for CRC patients who undergo curative colectomy, the patient's lymph node (LN) metastasis status is a crucial prognostic factor. Therefore, the American Joint Committee on Cancer (AJCC) recommends that for precise pathological staging, at least 12 LNs should be retrieved from the resected specimen for microscopic evaluation. However, the total number of retrieved LNs could be influenced by patient factors (such as age, sex, and intra‐abdominal anatomy), as well as the affected cancer characteristics, the operative procedure, and the LN isolation process from the resected specimen. In addition to these factors, obesity might have a significant influence on the outcome. Few reports have examined this subject, and most investigations have used body mass index (BMI), which is calculated by height and body weight, to define obesity. Few studies have defined obesity according to the quantity of visceral adipose tissue (VAT). In this study, we analyzed the effect of obesity, defined by BMI, VAT, and subcutaneous adipose tissue (SAT), on the number of retrieved LNs and the adequacy of LN retrieval (adequate, ≥12 LNs; inadequate, <12 LNs). We compared the http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Surgical Oncology Wiley

The impact of visceral adipose tissue amount on the adequacy of lymph node retrieval in colorectal cancer surgery

Loading next page...
 
/lp/wiley/the-impact-of-visceral-adipose-tissue-amount-on-the-adequacy-of-lymph-ZyUwvr0FKO
Publisher
Wiley Subscription Services, Inc., A Wiley Company
Copyright
© 2018 Wiley Periodicals, Inc.
ISSN
0022-4790
eISSN
1096-9098
D.O.I.
10.1002/jso.24876
Publisher site
See Article on Publisher Site

Abstract

INTRODUCTIONAs the obese population increases, patients who receive surgery for colorectal cancer (CRC) are more likely to be obese. Clinically, for CRC patients who undergo curative colectomy, the patient's lymph node (LN) metastasis status is a crucial prognostic factor. Therefore, the American Joint Committee on Cancer (AJCC) recommends that for precise pathological staging, at least 12 LNs should be retrieved from the resected specimen for microscopic evaluation. However, the total number of retrieved LNs could be influenced by patient factors (such as age, sex, and intra‐abdominal anatomy), as well as the affected cancer characteristics, the operative procedure, and the LN isolation process from the resected specimen. In addition to these factors, obesity might have a significant influence on the outcome. Few reports have examined this subject, and most investigations have used body mass index (BMI), which is calculated by height and body weight, to define obesity. Few studies have defined obesity according to the quantity of visceral adipose tissue (VAT). In this study, we analyzed the effect of obesity, defined by BMI, VAT, and subcutaneous adipose tissue (SAT), on the number of retrieved LNs and the adequacy of LN retrieval (adequate, ≥12 LNs; inadequate, <12 LNs). We compared the

Journal

Journal of Surgical OncologyWiley

Published: Jan 1, 2018

Keywords: ; ; ;

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off