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The effect of beclomethasone dipropionate aerosol on allergen induced nasal stenosis

The effect of beclomethasone dipropionate aerosol on allergen induced nasal stenosis Summary Nasal resistance to air flow has been used to evaluate the effect of beclomethasone dipropionate aerosol on allergen induced nasal stenosis. Sixteen patients with allergic‐rhinitis due to pollen were investigated in a randomized double‐blind cross‐over study with beclomethasone dipropionate aerosol and placebo aerosol. Only patients reacting to challenge were chosen. The study was carried out in the pollen‐free season. After I week on either active or placebo aerosol a basic resistance value was determined followed by allergen challenge. Nasal resistance was determined 15 min and 7 hr after challenge. The aerosols were changed and after another week the procedure was repeated. There was significant preference (P<0.01) for beclomethasone dipropionate aerosol. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Clinical & Experimental Allergy Wiley

The effect of beclomethasone dipropionate aerosol on allergen induced nasal stenosis

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Publisher
Wiley
Copyright
Copyright © 1975 Wiley Subscription Services, Inc., A Wiley Company
ISSN
0954-7894
eISSN
1365-2222
DOI
10.1111/j.1365-2222.1975.tb01865.x
Publisher site
See Article on Publisher Site

Abstract

Summary Nasal resistance to air flow has been used to evaluate the effect of beclomethasone dipropionate aerosol on allergen induced nasal stenosis. Sixteen patients with allergic‐rhinitis due to pollen were investigated in a randomized double‐blind cross‐over study with beclomethasone dipropionate aerosol and placebo aerosol. Only patients reacting to challenge were chosen. The study was carried out in the pollen‐free season. After I week on either active or placebo aerosol a basic resistance value was determined followed by allergen challenge. Nasal resistance was determined 15 min and 7 hr after challenge. The aerosols were changed and after another week the procedure was repeated. There was significant preference (P<0.01) for beclomethasone dipropionate aerosol.

Journal

Clinical & Experimental AllergyWiley

Published: Sep 1, 1975

References

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