Summary To evaluate the effects of age and diet on the oral glucose tolerance test (OGTT) in healthy ponies, OGTTs were performed on 2 groups of British native breed ponies (Group A: 7 foals (6–9 months), Group B: 7 mature individuals (6–13 years)) when maintained on either a high fibre pelleted ration only (Groups A and B) or a hay only diet (Group B). Plasma glucose response, following oral glucose administration, for Group A (basal plasma glucose concentration (Glu0) 4.6 ± 0.4 mmol/1 (mean ± s.d.) increasing to 11.5 ± 1.3 mmol/1 at 90 min) was significantly different (P<0.05) from that observed for Group B (Glu0 of 4.3 ± 0.2 mmol/1 increasing to 6.8 ± 1.3 mmol/1 at 90 min), when fed the same diet. For Group B ponies, the plasma glucose response, following oral glucose administration, was significantly different (P<0.05) when fed hay only (Glu0 4.6 ± 0.4 mmol/1 increasing to 9.6 ± 2.1 mmol/l at 150 min) compared to when fed the high fibre pelleted ration. These results indicate that both age and diet have a significant effect on plasma glucose concentrations measured during an OGTT.
Equine Veterinary Journal – Wiley
Published: Nov 1, 1997
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