Introduction Although a very useful and important group of medications used in equine medicine, glucocorticoids have been suggested by some authors to be associated with the risk of inducing acute laminitis when administered systemically (Lose 1980; Lawrence et al. 1985; Eustace and Redden 1990; Frederick and Kehl 2000; Ryu et al. 2004). This link has not been proven experimentally. Whether or not this might involve a direct effect of these drugs and, further, whether the risk is significant enough in the clinical setting to affect how and when these drugs are used, is currently a matter for debate. The report of a recent high-profile case, described in this issue (Dutton 2007), once again brings these questions into the spotlight. Evidence directly linking the administration of corticosteroids with the induction of laminitis is scarce. The reader is referred to previous reviews of the possible links between glucocorticoid therapy and laminitis (Johnson et al. 2002; Cornelisse and Robinson 2004). This review seeks to update the current evidence base on this subject, so that the potential risk of inducing laminitis by the systemic use of glucocorticoids can be more accurately assessed. Areas where further research is needed (epidemiological, clinical and/or on
Equine Veterinary Journal – Wiley
Published: Jan 1, 2007
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera