OBJECTIVES: To determine the relationships between recreational activity, house/yard work activity, work activity, and total physical activity and high levels of two peripheral blood markers of inflammation: interleukin‐6 (IL‐6) and C‐reactive protein (CRP). DESIGN: Cross‐sectional study. SETTING: Three communities (Durham, NC; New Haven, CT; and East Boston, MA). PARTICIPANTS: Eight hundred seventy persons aged 70 to 79 who were in the top third of community‐dwelling older persons with respect to physical and cognitive functioning. MEASUREMENTS: Blood levels of IL‐6 and CRP and self‐reported recreational activity, house/yard work activity, work activity, and total physical activity. RESULTS: The adjusted odds ratios (AORs) for individuals with high levels of recreational activity to have values in the top tertiles of IL‐6 and CRP were 0.65 (95% confidence interval (CI) = 0.48–0.87) and 0.70 (95% CI = 0.51–0.95), respectively. The AORs for those with a high level of house/yard work activity to have values in the top tertile of IL‐6 and CRP were 0.90 (95% CI = 0.67–1.20) and 0.70 (95% CI = 0.50–0.96), respectively. High levels of house/yard work and recreational activity were independently associated with lower risk of high CRP. CONCLUSION: The association between high levels of recreational activity and lower levels of the inflammatory markers IL‐6 and CRP suggests a mechanism for its protective effect and supports interventions that increase physical activity in older persons. Such potential benefits of increased physical activity on inflammatory markers will need to be confirmed in clinical trials.
Journal of American Geriatrics Society – Wiley
Published: Aug 1, 2003
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera