Synthesis and Evaluation of Some Novel 2‐Amino‐4‐Aryl Thiazoles for Antitubercular Activity

Synthesis and Evaluation of Some Novel 2‐Amino‐4‐Aryl Thiazoles for Antitubercular Activity A series of novel 2‐amino‐4‐aryl thiazoles were synthesized from α‐chloroacetophenone and thiourea at room temperature using acetone as solvent. The structures of synthesized compounds were confirmed by spectral data. All the compounds were evaluated for antitubercular activity by macro broth dilution method against Mycobacterium Tuberculosis H37Rv as standard strain. The synthesized compound displays notable antitubercular activity. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Heterocyclic Chemistry Wiley

Synthesis and Evaluation of Some Novel 2‐Amino‐4‐Aryl Thiazoles for Antitubercular Activity

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Publisher
Wiley Subscription Services, Inc., A Wiley Company
Copyright
© 2018 Wiley Periodicals, Inc.
ISSN
0022-152X
eISSN
1943-5193
D.O.I.
10.1002/jhet.3098
Publisher site
See Article on Publisher Site

Abstract

A series of novel 2‐amino‐4‐aryl thiazoles were synthesized from α‐chloroacetophenone and thiourea at room temperature using acetone as solvent. The structures of synthesized compounds were confirmed by spectral data. All the compounds were evaluated for antitubercular activity by macro broth dilution method against Mycobacterium Tuberculosis H37Rv as standard strain. The synthesized compound displays notable antitubercular activity.

Journal

Journal of Heterocyclic ChemistryWiley

Published: Jan 1, 2018

References

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