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R. Heumann, D. Lindholm, C. Bandtlow, M. Meyer, M. Radeke, T. Misko, E. Shooter, H. Thoenen (1987)
Differential regulation of mRNA encoding nerve growth factor and its receptor in rat sciatic nerve during development, degeneration, and regeneration: role of macrophages.Proceedings of the National Academy of Sciences of the United States of America, 84 23
James Turner, J. Blair, E. Chappel (1987)
Peripheral nerve implant effects on survival of retinal ganglion layer cells after axotomy initiated by a penetrating lesionBrain Research, 419
V. Perry (1979)
The ganglion cell layer of the retina of the rat: a Golgi studyProceedings of the Royal Society of London. Series B. Biological Sciences, 204
T. Ford-Holevinski, J. Hopkins, J. McCoy, B. Agranoff (1986)
Laminin supports neurite outgrowth from explants of axotomized adult rat retinal neurons.Brain research, 393 1
J. Sievers, B. Hausmann, K. Unsicker, M. Berry (1987)
Fibroblast growth factors promote the survival of adult rat retinal ganglion cells after transection of the optic nerveNeuroscience Letters, 76
H. Müller, P. Gebicke-Harter, D. Hangen, E. Shooter (1985)
A specific 37,000-dalton protein that accumulates in regenerating but not in nonregenerating mammalian nerves.Science, 228 4698
M. Hofer, Y. Barde (1988)
Brain-derived neurotrophic factor prevents neuronal death in vivoNature, 331
D. Gospodarowicz, G. Neufeld, Lothar Schweigerer (1986)
Molecular and biological characterization of fibroblast growth factor, an angiogenic factor which also controls the proliferation and differentiation of mesoderm and neuroectoderm derived cells.Cell differentiation, 19 1
F. Longo, M. Manthorpe, S. Skaper, G. Lundborg, S. Varon (1983)
Neuronotrophic activities accumulate in vivo within silicone nerve regeneration chambersBrain Research, 261
A. Baird, F. Esch, D. Gospodarowicz, R. Guillemin (1985)
Retina- and eye-derived endothelial cell growth factors: partial molecular characterization and identity with acidic and basic fibroblast growth factors.Biochemistry, 24 27
K. Tohyama, C. Idé (1984)
The localization of laminin and fibronectin on the Schwann cell basal lamina.Archivum histologicum Japonicum = Nihon soshikigaku kiroku, 47 5
S. Thanos, J. Vanselow (1989)
Adult retinal ganglion cells retain the ability to regenerate their axons up to several weeks after axotomyJournal of Neuroscience Research, 22
P. Richardson, T. Ebendal (1982)
Nerve growth activities in rat peripheral nerveBrain Research, 246
J. Johnson, Y. Barde, M. Schwab, H. Thoenen (1986)
Brain-derived neurotrophic factor supports the survival of cultured rat retinal ganglion cells, 6
J. Assouline, Peter Bosch, R. Lim, In Kim, Robert Jensen, N. Pantazis (1987)
Rat astrocytes and Schwann cells in culture synthesize nerve growth factor-like neurite-promoting factors.Brain research, 428 1
Korsching Korsching, Thoenen Thoenen (1985)
Nerve growth factor supply for sensory neurons: site of origin and competition with sympathetic neuronsNeurosci. Lett., 54
M. Vidal-Sanz, G. Bray, M. Villegas–Pérez, S. Thanos, A. Aguayo (1987)
Axonal regeneration and synapse formation in the superior colliculus by retinal ganglion cells in the adult rat, 7
M. Berry, L. Rees, J. Sievers (1986)
Regeneration of Axons in the Mammalian Visual System
G. Barbin, M. Manthorpe, S. Varon (1984)
Purification of the Chick Eye Ciliary Neuronotrophic FactorJournal of Neurochemistry, 43
Y. Barde, D. Edgar, H. Thoenen (1982)
Purification of a new neurotrophic factor from mammalian brain.The EMBO Journal, 1
By Abercrombie, And, M. Johnson (1946)
Quantitative histology of Wallerian degeneration: I. Nuclear population in rabbit sciatic nerve.Journal of anatomy, 80 Pt 1
R. Dantzer (1987)
FRUSTRATION, AGGRESSION AND DRUGSAggressive Behavior, 13
Bähr Bähr, Vanselow Vanselow, Thanos Thanos (1988)
In vitro regeneration of adult rat ganglion cell axons from retinal explantsExp. Brain Res.
S. Shyne-Athwal, G. Chakraborty, E. Gage, N. Ingoglia (1988)
Comparison of posttranslational protein modification by amino acid addition after crush injury to sciatic and optic nerves of ratsExperimental Neurology, 99
C. Bandtlow, R. Heumann, M. Schwab, H. Thoenen (1987)
Cellular localization of nerve growth factor synthesis by in situ hybridization.The EMBO Journal, 6
L. Needham, G. Tennekoon, G. McKhann (1987)
Selective growth of rat Schwann cells in neuron- and serum-free primary culture, 7
Ford‐Holevinski Ford‐Holevinski, Hopkins Hopkins, McCoy McCoy, Agranoff Agranoff (1986)
Laminin supports neurite outgrowth from explants of axotomized adult rat retinal neuronsDev. Brain Res., 28
Walter Bradley, A. Asbury (1970)
Duration of synthesis phase in neuilemma cells in mouse sciatic nerve during degeneration.Experimental neurology, 26 2
Assouline Assouline, Bosch Bosch, Lim Lim, Kim Kim, Jensen Jensen, Pantazis Pantazis (1987)
Rat astrocytes and Schwann cells in culture synthesize nerve growth factor‐like neurite‐promoting factorsDev. Brain Res., 31
S. Korsching, H. Thoenen (1985)
Nerve growth factor supply for sensory neurons: Site of origin and competition with the sympathetic nervous systemNeuroscience Letters, 54
K. So, A. Aguayo (1985)
Lengthy regrowth of cut axons from ganglion cells after peripheral nerve transplantation into the retina of adult ratsBrain Research, 328
M. Schwab, H. Thoenen (1985)
Dissociated neurons regenerate into sciatic but not optic nerve explants in culture irrespective of neurotrophic factors, 5
C. Barnstable, U. Dräger (1984)
Thy-1 antigen: A ganglion cell specific marker in rodent retinaNeuroscience, 11
M. Politis, M. Politis, Peter Spencer, Peter Spencer (1986)
Regeneration of rat optic axons into peripheral nerve graftsExperimental Neurology, 91
M. Schwab, Pica Caroni (1988)
Oligodendrocytes and CNS myelin are nonpermissive substrates for neurite growth and fibroblast spreading in vitro, 8
S. Thanos, M. Vidal-Sanz, A. Aguayo (1987)
The use of rhodamine-B-isothiocyanate (RITC) as an anterograde and retrograde tracer in the adult rat visual systemBrain Research, 406
Robert Rush (1984)
Immunohistochemical localization of endogenous nerve growth factorNature, 312
S. Korsching, H. Thoenen (1983)
Nerve growth factor in sympathetic ganglia and corresponding target organs of the rat: correlation with density of sympathetic innervation.Proceedings of the National Academy of Sciences of the United States of America, 80 11
R. Lindsay (1988)
Nerve growth factors (NGF, BDNF) enhance axonal regeneration but are not required for survival of adult sensory neurons, 8
C. Cornbrooks, D. Carey, J. McDonald, R. Timpl, R. Bunge (1983)
In vivo and in vitro observations on laminin production by Schwann cells.Proceedings of the National Academy of Sciences of the United States of America, 80 12
A. Johnson, C. Wigley, N. Gregson, J. Cohen, M. Berry (1988)
Neither laminin nor prior optic nerve section are essential for the regeneration of adult mammalian retinal ganglion cell axonsin vitroJournal of Neurocytology, 17
R. Heumann, S. Korsching, J. Scott, H. Thoenen (1984)
Relationship between levels of nerve growth factor (NGF) and its messenger RNA in sympathetic ganglia and peripheral target tissues.The EMBO Journal, 3
A peripheral nerve exudate, collected in situ from the proximal end of a severed rat sciatic nerve, can induce substantial axonal elongation from ganglion cells when tested on explanted adult rat retinae. The responsive cells are identified on the basis of their Thy 1.1 immunostaining properties. Similar outgrowth can be obtained from explants when the culture medium is supplemented with brain‐derived neurotrophic factor (BDNF). In addition, both BDNF and the sciatic nerve exudate can prevent ganglion cell degeneration as shown by the retrograde transport of a fluorescent dye that had been applied to the superior colliculus prior to explantation. The results demonstrate that soluble components, released by lesioned peripheral nerves, can effect adult retinal ganglion cells in a way that is reminiscent of that which has been described in vivo using sciatic nerve grafts after sectioning of the optic nerve. The molecular nature of these components is discussed.
European Journal of Neuroscience – Wiley
Published: Jan 1, 1989
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