wileyonlinelibrary.com/journal/ane Acta Neurol Scand. 2018;138:12–23.
© 2018 John Wiley & Sons A/S.
Published by John Wiley & Sons Ltd
1 | INTRODUCTION
Parkinson’s disease (PD) is one of the most common neurodegenerative
disorders, with a prevalence generally estimated at 0.3% of the entire
population in industrialized countries. It is the second most common
neurodegenerative disorder, after Alzheimer’s disease and its preva-
lence increases with age, reaching 1% in people over 60 years of age.
One of the main characteristics of PD is degeneration of
dopamine- producing neurons in Substantica Nigra par compacta
(SNc), which gives rise to the 4 essential features: bradykinesia
(or akinesia, or hypokinesia), tremor at rest, rigidity, and postural instabil-
ity. In addition, flexed posture and freezing (motor blocks) and many non-
motor symptoms are other common features of PD
such as loss of sense
of smell, constipation, orthostatic hypotension, sleep and mood disorders.
These problems together with the chronicity and progressive nature of the
illness itself may seriously hamper patients’ physical and mental health.
Studies on people suffering from PD were mainly based on a
neurological and psychiatric perspective. This perspective focused
Accepted: 29 March 2018
Subjective and psychological well- being in Parkinson’s Disease:
A systematic review
| D. Sarti
| C. Ruini
Department of Psychology, University of
Bologna, Bologna, Italy
Riminiterme Center of Rehabilitation,
F. Vescovelli, Department of Psychology,
University of Bologna, Bologna, Italy.
Objectives: The aim of this review is to summarize studies investigating subjective
and psychological well- being in patients with Parkinson’s disease (PD).
Materials and Methods: A systematic and integrative review according to PRISMA crite-
ria was performed with a literature search from inception up to September 2017 in mul-
tidisciplinary databases (PubMED, Scopus, Web of Knowledge) by combining together
key words related to PD and well- being. Studies were included if: their full- text was
available; they involved PD patients; focused on the selected positive dimensions; writ-
ten in English. Case studies, conference proceedings, abstract, dissertations, book chap-
ters, validation studies and reviews were excluded. Data extracted from the studies
included sample characteristics, the positive dimension investigated, type of measure,
study aims, design and results. One reviewer extracted details and commented results
with other reviewers. The studies’ quality was assessed following Kmet, Lee, and Cook.
Results: Out of 1425 studies extracted, 12 studies (9 quantitative, 2 qualitative, 1
mixed methods) involving 2204 patients with PD were included. Most of the studies
had a cross- sectional design and/or evaluated the effect of physical rehabilitation on
well- being. Articles documented that the illness could impair well- being for its progres-
sive impact on patients’ motor autonomy. Preserving motor and musculoskeletal func-
tioning facilitate patients’ experience of well- being, social contribution and the
maintenance of their job.
Conclusions: Research on positive resources in PD is still scarce compared to other
chronic illnesses. The few available investigations suggest the need of preserving
motor abilities by proper rehabilitation programs for maintaining and/or promoting
patients’ well- being and life engagement.
life satisfaction, Parkinson’s disease, physical therapy, rehabilitation, well-being