Strategies for Drug Encapsulation and Controlled Delivery Based on Vapor‐Phase Deposited Thin Films

Strategies for Drug Encapsulation and Controlled Delivery Based on Vapor‐Phase Deposited Thin... IntroductionDrug therapies require the active pharmaceutical ingredients (API) to reach the desired site of action and the success of the treatment is governed by the time the drug requires to reach the target, the amount of drug assembling at the target site as well as its residence time. Furthermore, considerations like administration route, processing, and storage of drug formulations need attention as only the combination of all these allows the achievement of successful medications ready for therapy, marketing, and help for patients. Very often, drug molecules well perform only when assistance from other substances is provided. These substances (i.e., excipients) limit processing issues, mechanical and chemical instabilities, dissolution problems, resorption problems, and poor bio‐availability or assist for better systemic circulation. Hence, the development of new therapeutic options is not limited to the synthesis and screening of new APIs, but also different administration routes and alternative dosage forms are extensively investigated. Generally, the latter is achieved by the engineering and processing of new excipients.Ever since medications were used, excipients are employed. Especially, the usage of macromolecules or polymers as fillers, gliding agent, disintegration agent, or protective coatings allow the preparation of solid state formulations like tablets, pellets, or powders. Developments http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Advanced Engineering Materials Wiley

Strategies for Drug Encapsulation and Controlled Delivery Based on Vapor‐Phase Deposited Thin Films

Loading next page...
 
/lp/wiley/strategies-for-drug-encapsulation-and-controlled-delivery-based-on-WHbc8uHi0z
Publisher
Wiley Subscription Services, Inc., A Wiley Company
Copyright
© 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
ISSN
1438-1656
eISSN
1527-2648
D.O.I.
10.1002/adem.201700639
Publisher site
See Article on Publisher Site

Abstract

IntroductionDrug therapies require the active pharmaceutical ingredients (API) to reach the desired site of action and the success of the treatment is governed by the time the drug requires to reach the target, the amount of drug assembling at the target site as well as its residence time. Furthermore, considerations like administration route, processing, and storage of drug formulations need attention as only the combination of all these allows the achievement of successful medications ready for therapy, marketing, and help for patients. Very often, drug molecules well perform only when assistance from other substances is provided. These substances (i.e., excipients) limit processing issues, mechanical and chemical instabilities, dissolution problems, resorption problems, and poor bio‐availability or assist for better systemic circulation. Hence, the development of new therapeutic options is not limited to the synthesis and screening of new APIs, but also different administration routes and alternative dosage forms are extensively investigated. Generally, the latter is achieved by the engineering and processing of new excipients.Ever since medications were used, excipients are employed. Especially, the usage of macromolecules or polymers as fillers, gliding agent, disintegration agent, or protective coatings allow the preparation of solid state formulations like tablets, pellets, or powders. Developments

Journal

Advanced Engineering MaterialsWiley

Published: Jan 1, 2018

Keywords: ; ; ; ; ; ;

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

Monthly Plan

  • Read unlimited articles
  • Personalized recommendations
  • No expiration
  • Print 20 pages per month
  • 20% off on PDF purchases
  • Organize your research
  • Get updates on your journals and topic searches

$49/month

Start Free Trial

14-day Free Trial

Best Deal — 39% off

Annual Plan

  • All the features of the Professional Plan, but for 39% off!
  • Billed annually
  • No expiration
  • For the normal price of 10 articles elsewhere, you get one full year of unlimited access to articles.

$588

$360/year

billed annually
Start Free Trial

14-day Free Trial