INTRODUCTIONFamily Adenoviridae, genus Adenovirus, human adenovirus types (HAdVs) are known to cause strong inflammatory responses, such as elevation of the white blood cell (WBC) count and C‐reactive protein (CRP), which sometimes leads to overuse of antibiotics. Differences in the immune responses to the various species of HAdV have not been well studied. Links between epidemiology and immune responses may provide clues to understanding the mechanisms underlying HAdVs' circulation patterns.Although HAdVs are one of the most common pathogens in young children, accounting for 10‐29% of upper respiratory infections, the diseases they cause are believed to be mild and self‐limiting. However, HAdVs sometimes cause outbreaks of severe disease not only in children, but also in adults. Understanding the circulation patterns of and inflammatory responses to HAdV in healthy children might have epidemiological significance since virus circulating in the normal population may serve as a reservoir for outbreaks. There have been, however, no reports that investigated community‐based epidemiology, including inflammatory testing for common HAdV respiratory disease in children.To address the above issue, we conducted a prospective study aimed at clarifying the circulation patterns and clinical/laboratory features of respiratory HAdV infections in children at a primary care clinic in a small community. Their
Journal of Medical Virology – Wiley
Published: Jan 1, 2018
Keywords: ; ; ; ;
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.
All for just $49/month
Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.
Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.
It’s easy to organize your research with our built-in tools.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera