Brain and Behavior. 2018;8:e 0 0967.
1 of 7
Sleep disturbances and depression severity in patients with
Daniel B. Kay
| Jared J. Tanner
| Dawn Bowers
provided the original work is properly cited.
©2018TheAuthors. Brain and BehaviorpublishedbyWileyPeriodicals,Inc.
Department of Clinical and Health
share a bidirectional association. This association may be greater in individuals who
are more vulnerable to the deleterious consequences of sleep disturbance and de-
pression severity. We investigated whether the association between sleep distur-
bances and depression severity is greater in patients with PD than in matched controls
Materials and Methods:The studysample(N = 98)included 50 patientswithidio-
pathic PD and 48 age-, race-,sex-, and education-matched controls. Sleep distur-
banceswere assessedusing self-reported totalsleep time(TST) on thePittsburgh
Sleep Quality Index, the sleep item on the Beck Depression Inventory, 2nd ed.
(BDI-II), and the Insomnia Severity Index total score. Depression severity was as-
was used to test whether the association between sleep disturbances and depression
severity was stronger in patients with PD.
with depression severity in the total sample, r
(94)=−0.35, p = .001; r
p < .001; r
(78)=−0.47,p < .001; r
(98)=0.46,p < .001,respectively.Theassociation
wasinMC,p < .05.
Conclusion:ShortTST maybe an important marker, predictor, or consequence of
1 | INTRODUCTION
Idiopathic Parkinson’s disease (PD) is one of the most common
neurodegenerative disorders, second only to Alzheimer’s disease.
disorder associated with nonmotor symptoms including sleep changes