INTRODUCTIONDopamine, 3,4‐dihydroxyphenyl ethylamine, is a neurotransmitter of great importance for the nervous system of biological organisms, it is involved in motor control, endocrine function, reward, emotion, and cognition. Cellular and brain metabolism of dopamine can be correlated with a number of neurodegenerative disorders such as attention deficit hyperactivity disorder, mood disorders, Parkinson, and Alzheimer. The currently available analytical methods for dopamine determination in pharmaceutical samples and biological fluids including spectrophotometry, liquid chromatography, chemiluminescence, capillary electrophoresis, and electrochemical methods. However, aside from electrochemical detection, most of the procedures generally involve a time‐consuming sample pretreatment step and long analysis times and are relatively expensive. Therefore, the development of electrochemical biosensor has proven to be an attractive alternative for the determination of DA in the presence of interfering compounds due to their high sensitivity and selectivity, fast detection, low detection limits.Quantum dots (QDs), are semiconducting nanoparticlesas, that usually consist of group IIB‐VIB or IIIB‐VB elements and are diameter stable at 2‐20 nm, have exhibit excellent optical and electro‐optical properties due to their quantum size effect, surface effect, and dielectric confinement effect. As a novel member of carbon family, QDs have been widely used in bioanalytical research, however, numerous studies only focus on the
Journal of Clinical Laboratory Analysis – Wiley
Published: Jan 1, 2018
Keywords: ; ;
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