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Role of quantitative intravoxel incoherent motion parameters in the preoperative diagnosis of nodal metastasis in patients with rectal carcinoma

Role of quantitative intravoxel incoherent motion parameters in the preoperative diagnosis of... ORIGINAL RESEARCH Role of Quantitative Intravoxel Incoherent Motion Parameters in the Preoperative Diagnosis of Nodal Metastasis in Patients With Rectal Carcinoma 1 1 1 2 Lin Qiu, MS, Xiao-Ling Liu, BS, Si-Run Liu, MS, Ze-Ping Weng, MS, 1 1 1 Xiao-Qiao Chen, BS, You-Zhen Feng, BS, Xiang-Ran Cai, MD, * and Chang-Yu Guo, MS * Purpose: To evaluate the diagnostic value of intravoxel incoherent motion imaging (IVIM) in differentiating metastatic and nonmetastatic lymph nodes in patients with rectal carcinoma. Materials and Methods: In all, 68 patients with histologically proven rectal carcinoma underwent an IVIM sequence (b 5 0, 25, 50, 75, 100, 150, 200, 400, 600, 800, 1000, 1200, 1500, and 2000 s/mm ) on a 3.0T MRI scanner. The IVIM parameters (D, D*, f, and apparent diffusion coefficient [ADC] values) in metastatic and nonmetastatic lymph nodes were measured and calculated. Receiver-operating characteristic (ROC) analyses were conducted to determine the optimal thresholds, the sensitivities, and specificities for differentiation. Results: Mean D, f, and ADC values of metastatic lymph nodes were significantly greater than those of the normal lymph nodes (P < 0.01), whereas the mean D* value of metastatic lymph node was statistically lower (P 5 0.03). The AUC, http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Magnetic Resonance Imaging Wiley

Role of quantitative intravoxel incoherent motion parameters in the preoperative diagnosis of nodal metastasis in patients with rectal carcinoma

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References (41)

Publisher
Wiley
Copyright
© 2016 Wiley Periodicals, Inc.
ISSN
1053-1807
eISSN
1522-2586
DOI
10.1002/jmri.25250
pmid
27019309
Publisher site
See Article on Publisher Site

Abstract

ORIGINAL RESEARCH Role of Quantitative Intravoxel Incoherent Motion Parameters in the Preoperative Diagnosis of Nodal Metastasis in Patients With Rectal Carcinoma 1 1 1 2 Lin Qiu, MS, Xiao-Ling Liu, BS, Si-Run Liu, MS, Ze-Ping Weng, MS, 1 1 1 Xiao-Qiao Chen, BS, You-Zhen Feng, BS, Xiang-Ran Cai, MD, * and Chang-Yu Guo, MS * Purpose: To evaluate the diagnostic value of intravoxel incoherent motion imaging (IVIM) in differentiating metastatic and nonmetastatic lymph nodes in patients with rectal carcinoma. Materials and Methods: In all, 68 patients with histologically proven rectal carcinoma underwent an IVIM sequence (b 5 0, 25, 50, 75, 100, 150, 200, 400, 600, 800, 1000, 1200, 1500, and 2000 s/mm ) on a 3.0T MRI scanner. The IVIM parameters (D, D*, f, and apparent diffusion coefficient [ADC] values) in metastatic and nonmetastatic lymph nodes were measured and calculated. Receiver-operating characteristic (ROC) analyses were conducted to determine the optimal thresholds, the sensitivities, and specificities for differentiation. Results: Mean D, f, and ADC values of metastatic lymph nodes were significantly greater than those of the normal lymph nodes (P < 0.01), whereas the mean D* value of metastatic lymph node was statistically lower (P 5 0.03). The AUC,

Journal

Journal of Magnetic Resonance Imaging – Wiley

Published: Oct 1, 2016

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